Example sentences for: epk

How can you use “epk” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The eukaryotic protein kinase (EPK) family is one of the largest protein families represented in the human genome.

  • Identifiers ending in '_DOM2' indicate the second EPK domain from a protein which contains two separate EPK domains.

  • EPK family members which have been previously named as EPKs, categorized into an EPK subfamily, or whose description clearly suggests they are EPK family members were assigned a status of 1. EPKs whose names or description suggest that the annotator recognized the existence of the protein without giving a clear indication of its similarity to EPKs beyond a similarity score calculated by automated annotation processes were assigned a status of 2. EPKs whose GenBank annotation did not clearly delineate the encoded protein or its potential function were assigned a status of 3. The tableis presented in comma separated values (csv) format, and is best viewed with a spreadsheet program such as Microsoft Excel.

  • We empirically determined cut-off scores for these comparisons that lead to rejection of most independently verified pseudogenes and simulated poor-quality sequences, while retaining all known EPK genes and verifiable novel EPK sequences (data not shown).

  • If the BLASTN alignment spanned at least 240 nucleotides, and the percentage identity in the BLASTN comparison exceeded that for the corresponding segment of the TBLASTX comparison by more than 10%, this was taken as evidence that the protein potentially encoded by the novel sequence was under less selective pressure than is seen for known EPK family members, and is therefore probably a pseudogene or sequencing artifact.


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