Example sentences for: epistasis

How can you use “epistasis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We then estimated the prediction error based onthe average predictive ability across the 10 cross-validations forall 100 data sets generated under each epistasis model.

  • Thus, a highcross-validation consistency (~10) lends support to that SNP beingimportant for the epistasis model.

  • Moreover, in two of the studies on compensation, it was shown that the compensatory mutations had occurred outside the gene that was debilitated [ 58 59 ] . Therefore, the observed patterns of epistasis and compensation do not merely reflect the robustness of individual RNA and protein molecules to multiple mutations (as described above), but must indicate more general features of their genomes.

  • However, our findings do indicate that compensatory mutations can play a major role in producing antagonistic epistasis and thus slowing the decay in mean fitness under random mutation accumulation.

  • Hence, evolutionary hypotheses that depend crucially on the sign of epistasis, including certain theories on the evolution of recombination [ 12 13 14 15 ] and on the speed of mutation accumulation in asexual populations [ 16 17 18 ] , will also depend on the density distribution of fit genotypes, and on the topology of those regions of genotype space into which populations move under the pressures of mutation and selection.


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