Example sentences for: epistasis

How can you use “epistasis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The removal of compensatory mutations causes a pronounced upward shift of β toward more synergistic epistasis.

  • Hence, evolutionary hypotheses that depend crucially on the sign of epistasis, including certain theories on the evolution of recombination [ 12 13 14 15 ] and on the speed of mutation accumulation in asexual populations [ 16 17 18 ] , will also depend on the density distribution of fit genotypes, and on the topology of those regions of genotype space into which populations move under the pressures of mutation and selection.

  • We then estimated the prediction errorof GPNN based on the average prediction error across the 10 cross-validationsfor all 100 data sets for each epistasis model.

  • In order to analyze the topology and structure of fitness landscapes, and assess their effect on epistasis, we need a system where each sequence in a well-defined space is assigned a unique fitness that is independent of the frequency of other genotypes in the population.

  • [ 1 ] ). By contrast, if deleterious mutations interact so that their combined effect is smaller than expected under the multiplicative model, then epistasis is called antagonistic (or positive in the terminology of Phillips et al.)


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