Words similar to episomal

Example sentences for: episomal

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GAL1 promoter in a centromeric or episomal plasmid, respectively, indirect immunofluorescence of HA-Ppt1p or direct fluorescence from EGFP-Ppt1p showed that both proteins were also localized throughout the cell.
These observations are consistent with earlier studies that a punctate signal is representative of integration and a diffuse signal of episomal HPV, and with the theory that integration is an important factor in lesion progression [ 2 12 ] . The data suggest the optimized method may be useful in screening CIN lesions for integration.
'Diffuse' signals (indicative of episomal HPV), 'diffuse' and 'punctate', or 'punctate' signals alone were demonstrated amongst pre-invasive lesion samples (Figure 2A,2Band 2C).
A possible explanation maybe that that ~8 kilo-base single/low-copy episomal HPV sequences may be subject to relatively more degradation and loss from tissues during routine processing than HPV DNA that is physically integrated into the human chromosome (~50 - 250 mega-base pairs).
[ 13 ] . HPV was not detected by the assay in basal/parabasal cells of (non-condylomatous) CIN I lesions (> 30 examined; unless HPV-16 positive [ 2 ] ) suggesting low-copy number episomal HPV was not detectable and indicating a limit to the sensitivity of the assay.