Words similar to enzyme-bound

Example sentences for: enzyme-bound

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Although the estimated concentration, in mice and human cells, of intracellular ThDP is about 30 μM, much of this is found in a low turnover pool representing enzyme-bound ThDP [ 4 17 ] . The estimated concentration of free cytosolic ThDP available for intracellular transport is about 10% of the total concentration and thus 2 to 3 μM [ 4 17 18 ] . Hence the physiological significance of the mitochondrial ThDP uptake just decribed is uncertain.
The intracellular concentration of ThDP has been estimated at 30 μM, with only about 7 percent being free cytosolic and the remainder being enzyme-bound with much of this within mitochondria [ 4 5 ] . Previous findings indicate a complex, cell-type dependent regulation of compartmentalization and intracellular pools of thiamine and its phosphorylated derivatives in response to fluctuating extracellular thiamine levels [ 4 5 6 ] . Hence, thiamine transport, including that by mitochondria, is of interest.