Example sentences for: enzyme-

How can you use “enzyme-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This is consistent with an early observation of dissociation of the enzyme-DNA complex in high salt upon addition of Mg 2+ [ 13 ] . It has also been reported [ 14 ] that addition of Mg 2+was apparently not required for observation of this reversal of cleavage.

  • Removal of negative supercoils from DNA by bacterial type IA topoisomerase involves the following steps: (1) binding of the enzyme to the junction of double-stranded and single-stranded DNA [ 8 ] ; (2) cleavage of a single-strand of DNA near the junction with cleavage sequence preference of a cytosine in the -4 position to form the covalent intermediate [ 9 10 ] ; (3) conformational change of the covalent enzyme-DNA complex to result in physical separation of the 5' phosphate covalently linked to the active tyrosine, and the 3' hydroxyl of the cleaved DNA; (4) passage of the complementary single strand through the break; (5) enzyme conformational change to bring the 5' phosphoryl end back into the proximity of the 3' hydroxyl group of the cleaved DNA; (6) religation of the phosphodiester bond.


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