Words similar to ectopic
Example sentences for: ectopic
How can you use “ectopic” in a sentence? Here are some example sentences to help you improve your vocabulary:
We have previously shown that both net1 tab 2-1and CDC14 TAB 6-1efficiently bypassed the mitotic arrest caused by Tem1-depletion [ 15 18 ] . Furthermore, bypass was accompanied by ectopic Sic1 accumulation and Clb2 degradation.
As an alternative to the forced expression of ectopic PTEN in anchorage-independent, PTEN-negative tumor cells, our study has focused on the regulation of endogenous PTEN in anchorage-dependent mouse and human fibroblasts.
p27 specifically inhibits CDKs, which mediate entry into S phase [ 10 11 ] . The level of p27 is higher in quiescent than in proliferating cells, and this increase in p27 abundance is required for an effective cell cycle exit [ 12 ] . The cell cycle-dependent variations in p27 levels are not reflected by similar changes in p27 mRNA [ 13 ] . Many aggressive prostate cancers display decreased p27 protein levels in the presence of high p27 mRNA [ 14 ] , suggesting that p27 depletion may result from ectopic proteolysis.
Our results rather indicate that ectopic TAF II 135 expression acts at an early stage to impair primitive endoderm differentiation, but does not prevent the T-RA-induced changes which render the cells bt 2 cAMP responsive.
Although Cdc5 activity (1) is necessary to free nucleolar Cdc14 in late mitosis, (2) can elicit ectopic release of Cdc14 in pre-anaphase cells when overproduced, (3) regulates the phosphorylation state of Net1 during anaphase, and (4) can disassemble native and recombinant RENT complexes in vitro by phosphorylating Net1, a combination of in vivo and in vitro phosphosite mapping and mutagenesis experiments suggest that Cdc5 mediates exit from mitosis primarily by phosphorylating targets other than Net1.
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