Words similar to ectopic
Example sentences for: ectopic
How can you use “ectopic” in a sentence? Here are some example sentences to help you improve your vocabulary:
For example, mouse embryonal stem (ES) cells with homozygous deletion of the PTEN gene exhibit increased anchorage-independent growth as compared to normal ES cells [ 12 ] . Similarly, transfer of a wild type PTEN gene into anchorage-independent human glioblastoma cells (which lack functional PTEN), results in their greatly reduced ability to form colonies in soft agar [ 4 5 6 ] . The interpretation of these latter findings, however, is complicated by the strong anti-proliferative effects of PTEN even in monolayer culture, which is consistently observed when the wild type version of this gene is introduced into PTEN-negative tumor cells [ 4 6 7 8 9 10 18 33 ] . Moreover, in human glioma and breast cancer cell lines, the ectopic expression of wild type PTEN leads to anoikis, which is apoptosis initiated by the disruption of cell matrix-interactions [ 23 34 35 36 ] .
These results suggest that the combination of ectopic Msx1 expression and serum stimulation can induce differentiated muscle cells to dedifferentiate into proliferating multipotent progenitor cells.
CV-1 cells do not express endogenous AR, therefore, all experiments were performed in the presence of ectopic wild-type human AR.
C57mg cells were chosen since they become transformed by ectopic expression of Wnt-1 and by loss of function of Wnt-5a [ 12 15 16 ] . In addition, Wnt-5a/Rfz-2 C57mg cells exhibited phenotypic differences from wt C57mg cells (see results).
In F9 cells with constitutive ectopic expression of TAF II 135, targeted degradation is delayed, primitive endodermal differentiation is impaired and a novel differentiation pathway is induced.
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