Words similar to ecams
Example sentences for: ecams
How can you use “ecams” in a sentence? Here are some example sentences to help you improve your vocabulary:
IL-10 deficiency in colitis increases expression of several ECAMs including ICAM-1, VCAM-1 and MAdCAM-1 [ 60 ] . We performed an experiment, where under non-stimulated conditions only 55.
Therefore, these data suggest that the reduction of TK-1 adhesion is approximately 84% (42%/50%) MAdCAM-1 dependent, and that the remaining 16% of adhesion depends on other ECAMs, (such as ICAM-1).
There are at least two regulating pathways in ECAM expression, one is a cytokine-dependent pathway which is widely studied and the other is cytokine-independent [ 58 ] . IL-10 apparently prevents cytokine-induced NF-kB binding activity to the ECAM promoter [ 59 ] and blocks the excessive expression of ECAMs in cytokine-mediated inflammatory conditions.
ECAMs support several forms of leukocyte adhesion including rolling, firm adhesion and extravasation [ 1 ] . Infiltration of tissues by leukocytes is a common hallmark of many chronic inflammatory states that include the inflammatory bowel diseases (IBD), ulcerative colitis (UC), and Crohn's disease (CD).
In the setting of IBD, the expression of ECAMs like ICAM-1, VCAM-1, and MAdCAM-1 (mucosal addressin cell adhesion molecule-1) is observed in experimental models of colitis, [ 2 3 4 5 ] and also within the inflamed human colon in Crohn's disease and ulcerative colitis [ 6 7 ] .
Loading...