Words similar to dysregulated

Example sentences for: dysregulated

How can you use “dysregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

Tyrosine kinase activity is tightly regulated in normal cells, but is dysregulated due to mutation in some cancers, including lung cancer, resulting in enhanced proliferation and survival of cancer cells.
In rodents, resistin is derived exclusively from adipocytes [11,12], circulates at increased levels in obese animals [11], and causes dysregulated hepatic glucose production, leading to insulin resistance [13,14].
At the skeletal site of metastatic invasion, the bone metabolism is dysregulated and bone resorption or bone formation, or both, is upregulated.
Although K562 cells are derived from leukemia, among the genes showing altered regulation were several that are also dysregulated in breast cancer, including c- myc and cyclin D2; their altered expression was verified by real-time PCR.
The findings presented here, suggesting that different ECM signaling pathways are active in different cancers, could have important clinical implications, as knowledge of the specific pathways dysregulated in a particular cancer may be valuable for devising effective therapy that targets those pathways.