Words similar to dysregulation
Example sentences for: dysregulation
How can you use “dysregulation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Several studies have indicated that T helper (Th1) immune response has important roles in the development of IBD [ 48 49 50 ] . Moreover, dysregulation of cytokine networks is involved in Th1-dominant immune responses in IBD [ 48 49 50 ] . Among the Th1 cytokines, TNF-α is thought to be perhaps the most important cytokine responsible for driving the onset and evolution of IBD.
Based on the observations that: 1. cholesterol oxides cause PCD but the involvement of MAP kinases remains to be investigated; 2. PPARs are important in atherosclerosis but the effect of PPAR activation on cholesterol oxide induced PCD has not been determined, this study was designed to test if a dysregulation of MAP kinases was associated with the cholesterol oxide induced PCD, and to determine if PPAR activation could modulate the cholesterol oxide induced PCD.
Abnormalities of the peripheral vasculature responses to acetylcholine have been previously described in Fabry disease together with nitric oxide pathway dysregulation [ 5 9 ] suggesting participation of non-NO regulation of vascular tone.
As a consequence, osteoclast dysregulation leads to osteoporosis (decreased bone mass caused by excess osteoclast activity) or to osteopetrosis (increased bone mass caused by insufficient osteoclast activity).
The second set of observations indicate that reactive oxygen species (ROS) activate PLD2 in a PKC-dependent manner [ 9 ] . There is much evidence that ROS generation is upregulated in AD brain [ 42 ] . Thus, it is possible that PLD2 may be activated in this disease resulting, perhaps, in dysregulation of PC metabolism.
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