Words similar to dysgenic

Example sentences for: dysgenic

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These controls indicated that non-transfected dysgenic myotubes are low-background cells that do not express voltage-activated Ca 2+signals of major consequence for the present studies.
Numerous observations have lent support to this view, and especially significant are the functional expression studies in dysgenic myotubes lacking α 1S . The dysgenic myotube is devoid of L-type Ca 2+current, charge movements and EC coupling.
Expression of a frame-shift mutation of α 1Sin dysgenic myotubes
Previous studies showed this choice of pulse protocol and internal and external solutions resulted in nifedipine-sensitive charge movements of a magnitude ∼ 5 fold larger than those detected in dysgenic myotubes lacking α 1S [ 29].
Hence the signaling mechanism, like that reported in normal myotubes and dysgenic myotubes expressing wt-α 1S , was Ca 2+entry independent [ 29 ] . We also expressed fs-α 1S in cultured myotubes from two available gene knock-out (KO) mice, lacking the endogenous β1a isoform of the skeletal muscle DHPR [ 30 ] and lacking RyR1 [ 31 ] . As shown in Fig.