Words similar to dysgenesis

Example sentences for: dysgenesis

How can you use “dysgenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

These genes include PITX2, PITX3, PAX6, FOXC1 (previously known as FKHL7 and FREAC3), Foxc2 and FOXE3 [ 4 5 6 7 8 9 ] . Activity levels for these transcription factors normally associated with diploid gene dosage are important for normal ocular development, with heterozygosity for null mutations in most of these genes causing anterior segment dysgenesis.
These experiments will enhance understanding of the developmental processes involved in anterior segment formation, and glaucomas associated with anterior segment dysgenesis.
Series of subjects with gonadal dysgenesis, and isolated cases of Klinefelter's syndrome associated with rheumatic/autoimmune diseases (RAD), suggest a relation between these clinical conditions [ 2, 3].
For general anterior segment development, this is supported by the observations that genetic deficiency of transcription factors such as PAX6, PITX2, FOXC1 [ 44, 45], and LMX1B that are expressed in the periocular mesenchyme results in anterior segment dysgenesis in both humans and mice [ 46, 47, 48, 49, 50, 51, 52, 53, 54].
Thus, aberrations of both neural crest and mesoderm cell migration or differentiation may contribute to anterior segment dysgenesis and glaucoma.