Words similar to duplicon

Example sentences for: duplicon

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The second duplicon recognized within the 600 kb sub-interval was originally described as the Golgin-Linked-to-PML (promyelocytic leukemia) duplicon, or GLP duplicon, by Gilles et al . [ 18 ] and subsequently described as LCR15 by Pujana et al . [ 19 ] , Gratacos et al . [ 20 ] and Pujana et al.
Interestingly, the extent of the segmental duplications in the 1 Mb region examined was restricted to the clones that showed the dual FISH signal in PTR XVp and XVq and each clone that produced dual FISH signals contained a GLP/LCR15 duplicon by sequence analysis (Figure 4).
However, there is highly significant homology over ~100-kb of sequence from assembly contig NT_035325 mapping to 15q26, where LCR-15 duplicon sequences have been reported [ 18 ] . These sequences appear to correspond to the LCR15 class of duplicons, based on sequence content.
3 previously described by Riley et al . [ 17 ] , and several copies of a duplicon described as Golgin-linked-to-PML (GLP) [ 18 ] and as LCR15 [ 19 20 21 ] . A third, previously undetected, potential segmental duplication was identified in the proximal third of the 600 kb region (Figure 4, indicated by the asterisk).
With our results indicating the CHRNA7 sequence is single copy in the chimpanzee genome and thus unlikely to be involved in the inversion, the GLP/LCR15 duplicon is therefore the best candidate sequence for being present at the site of the pericentric inversion.