Example sentences for: dr-

How can you use “dr-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These results show that the negative effects of rexinoids on TCPOBOP and androstanol signaling observed with the DR-5 site from the RARβ promoter are not observed with the DR-4 and ER-6 sites from the CYP promoters.

  • Phenobarbitol and phenobarbitol-like substances activate CAR-RXR heterodimers (CAR, constitutive androstane receptor), that bind DR-4 response elements on the Cyp 2 promoter.

  • PPREs are direct repeats (DR) of a hexanucleotide sequence AGGTCA separated by one nucleotide and are therefore referred to as a DR-1 response element [ 30 ] . PPARα and PPARγ play critical roles in the catabolism and storage of FA, whereas the function of PPARδ is less certain.

  • In contrast to the results with the DR-5 site, but in agreement with the biochemical results, LG1069 alone had a stimulatory effect on the ER-6 CAR response element from the promoter of the CYP3A4 gene (Fig.

  • Cyps 3 and 4 are activated by PXR-RXR (PXR, pregnane X receptor) and PPARα-RXR, respectively, also binding DR-4 response elements in both cases.


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