Words similar to dr-
Example sentences for: dr-
How can you use “dr-” in a sentence? Here are some example sentences to help you improve your vocabulary:
The βRARE-TK-Luc reporter plasmid with three copies of the DR-5 motif from the promoter of the mouse RARβ2 gene has been described previously, as has the CYP2B10-TK-Luc reporter with two copies of the DR-4 type elements from the promoter of the mouse CYP2B10 gene and the CYP3A4-TK-luc reporter with three copies of the ER-6 element from the human CYP3A4 promoter [ 16 ] . Expression vectors for full length mCAR and RXR proteins were as described [ 9 ] . The cdm8-mCARΔ8 deletion construct containing a deletion of the last 8 amino acids and the mutant with 2 helix 3 mutations (F171L, I174A) that block ligand binding and response have been described previously [ 16 ] , as has the cdm8-RXRΔ19 construct with a deletion of the last 19 amino acids [ 3 ] .
HNFs may compete with PPARs for binding to DR-1 elements.
In contrast to the results with the DR-5 site, but in agreement with the biochemical results, LG1069 alone had a stimulatory effect on the ER-6 CAR response element from the promoter of the CYP3A4 gene (Fig.
Initial studies were based on a well characterized binding site for CAR/RXR heterodimers, the DR-5 element from the promoter of the retinoic acid receptor β2 isoform [ 8 9 16 ] . In agreement with the biochemical results, the rexinoid blocked both the stimulatory effect of the agonist and the inhibitory effect of the inverse agonist on this element (Fig.
Phenobarbitol and phenobarbitol-like substances activate CAR-RXR heterodimers (CAR, constitutive androstane receptor), that bind DR-4 response elements on the Cyp 2 promoter.
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