Words similar to drb
Example sentences for: drb
How can you use “drb” in a sentence? Here are some example sentences to help you improve your vocabulary:
To determine whether flavopiridol affects transcription globally, we compared the gene expression profile of flavopiridol treatment with the gene expression profiles induced in OCI-Ly3 cells by treatment with two well-studied transcriptional inhibitors, actinomycin D and DRB.
Although no murine knockouts of subunits of P-TEFb have been reported, DRB and flavopiridol, two ATP analogs that inhibit the kinase activity of CDK9, can inhibit nearly all transcription by RNAPII in human cells [29].
The following additional data files containing the primary data for the figures are included with this article: Figure 1a, flavopiridol titration ( Excel csv file); Figure 1c, Cdk inhibitors ( Excel csv file); Figure 2a, flavopiridol, actinomycin D and DRB ( Excel csv file); Figure 3, half-lives of well-measured genes ( Excel csv file); Figure 4a, proliferation genes ( Excel csv file); Figure 4b, anti-apoptotic genes ( Excel csv file); Figure 4d, induced genes in OCI -Ly3 cells ( Excel csv file); Figure 5c, highly induced genes in PBMC ( Excel csv file); Figure 5d, highly induced chemokines, cytokines and their receptors ( Excel csv file).
Using DNA microarrays, we found that flavopiridol inhibited gene expression broadly in a manner highly related to other transcription inhibitors such as actinomycin D and 5,6-dichloro-1-β-D-ribofuranosyl-benzimidazole (DRB).
The K d[app] for DEK binding to DQB is approximately four times that for the DQA1 sequences, whereas the K d[app] for DEK binding to the DRB Y-box sequences, especially the
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