Example sentences for: dqa

How can you use “dqa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 3a, lanes 3 and 4), whereas unlabeled DQA1*0501 Y-box sequence competed less well (Fig.

  • Further characterization of rDEK binding to the polymorphic DQA1*0501 Y-box sequence and to the consensus ( HLA-DRA ) Y-box sequence establishes a relative hierarchy of DEK binding activity (Fig.

  • The similarity of the DQA1*0101 Y-box sequence to the HIV-2 DEK-binding site (see Fig.

  • The DQA1*0501 promoter region (QAP 4.1), in which a single-base-pair polymorphism in the Y box significantly diminishes transcriptional activity [ 33 ] , is a component of the so-called susceptibility haplotype for autoimmune disease.

  • Finally, DEK binds differentially to specific Y-box sequences found in HLA-DQA1(*0101 and *0501 alleles) and HLA-DRA , consistent with observations of DQA1 gene-specific cell-surface expression [ 36 ] and allele-specific promoter activity [ 33 ] . The specificity of rDEK binding to these and other, related Y-box sequences (including HLA-DQB and HLA-DRB alleles associated with the DR4 haplotype) may correlate with a predisposition to autoim-mune disease seen with certain HLA haplotypes.


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