Example sentences for: dqa
How can you use “dqa” in a sentence? Here are some example sentences to help you improve your vocabulary:
We have previously shown that activation of promyeloid cells causes dephosphorylation of DEK and diminished DEK binding to the HIV-2 long terminal repeat [ 16 17 32 ] . In this study, we show that rDEK can bind to the DQA1 Y box, and that DEK in nuclear extracts participates in the DQA1 Y-box binding complex in vitro . Thus, we propose a model in which intracellular signaling modulates the ability of DEK to bind DNA, causing alteration of MHC class II transcription.
As shown in Table 1, DEK binds more strongly to Y-box sequences in either DQA1 allele than it does to any of the other DR - or DQ -related Y-box sequences.
5a, lanes 9-10) competes only slightly less well than does DQA1*0101 , indicating that a change in the residue at position 7 does not prevent rDEK binding.
Once again, the A-to-G substitution at position 3 in the Y box appears to strengthen DEK binding to the DQA1 Y box in comparison with the DRA Y box; allelic variation in the nucleotide at position 7 in the Y-box sequence (as in DQA1*0501 and in the DR4-associated
Competition EMSAs demonstrated sequence-specificity of the DQA1*0101 Y-box binding activity (Fig.
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