Example sentences for: dqa

How can you use “dqa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Electrophoretic patterns with a probe corresponding to the DQA1*0501 Y-box sequence, which diverges from the DQA1*0101 Y-box sequence by a single base pair within the highly conserved reverse CCAAT sequence, appear to vary with the cell type, and binding appears weaker than with the DQA1*0101 probe (see Fig.

  • Finally, DEK binds differentially to specific Y-box sequences found in HLA-DQA1(*0101 and *0501 alleles) and HLA-DRA , consistent with observations of DQA1 gene-specific cell-surface expression [ 36 ] and allele-specific promoter activity [ 33 ] . The specificity of rDEK binding to these and other, related Y-box sequences (including HLA-DQB and HLA-DRB alleles associated with the DR4 haplotype) may correlate with a predisposition to autoim-mune disease seen with certain HLA haplotypes.

  • It binds least well to the DRA (consensus) Y-box motif, with a K d[app] that is approximately five times that for the DQA1 sequences.

  • The similarity of the DQA1*0101 Y-box sequence to the HIV-2 DEK-binding site (see Fig.

  • Once again, the A-to-G substitution at position 3 in the Y box appears to strengthen DEK binding to the DQA1 Y box in comparison with the DRA Y box; allelic variation in the nucleotide at position 7 in the Y-box sequence (as in DQA1*0501 and in the DR4-associated


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