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Example sentences for: dpssm

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A similar secondary structure pattern is also observed in several other ligand-binding domains such as the PAS, GAF, profilin and probably even the CACHE domains [ 10 ] . Sequence-structure threading using the 3DPSSM method detected the PAS domain (Photoactive yellow protein PDB: 1drm) with marginally significant scores (.5, 50-70% probability of correct fold prediction).
Previously known, conserved domains were identified using PSI-BLAST derived profiles for them, with the RPS-BLAST program [ 45 ] . Sequence-structure threading was performed using the 3DPSSM server http://www.sbg.bio.ic.ac.uk/~3dpssm/.
Both 3DPSSM and PSIPRED gave hits (E-value approximately 0.05 for 3DPSSM and probability of matching approximately 0.8 for PSIPRED) that implied a 90% certainty of the KilA-N domain adopting the same fold as the APSES domain (PDB 1bm8/1bm1).
Additionally, the 3DPSSM threading also suggested that the LAGLIDADG endonuclease domain [ 18] (E-value 0.2; approximately 80% certainty) shared a common fold with the KilA-N proteins.