Example sentences for: domain

How can you use “domain” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus c-crk interacts constitutively with downstream effectors such as C3G via its SH3 domains, and interacts in a phosphotyrosine dependent fashion with tyrosine phosphorylated receptors using its SH2 domain [ 39 ] . To analyze downstream signals regulated by these adaptor proteins, investigators have developed methods that target them to distinct cellular membrane compartments by using heterologous targeting sequences.

  • It has been suggested that the stability of the dimer is related to the buried surface area between the two subunits [ 11 12 ] . In the nevirapine-bound HIV-1 RT crystal structure, the total contact surface area between the subunits is approximately ~4600 Å 2. The two major contact regions between the subunits which provide it stability are their connection subdomains and the thumb of p51 and RNase H domain of p66.

  • Indeed, the potential in vitro binding of the amino-terminus of Rlk to the SH3 domain of Grb2 hints of similar protein interactions.

  • EC, endothelial cell; MMP, matrix metalloproteinases; 3D, three-dimensional; KDR, kinase domain receptor; SSHDD, suppression subtractive hybridization followed by differential display; VE-cadherin, vascular endothelial-cadherin; PMA, phorbol 12-myristate 13-acetate; VEGF, vascular endothelial growth factor; bFGF, basic fibroblast growth factor.

  • Before use in PSI-BLAST searches, the PRC domain was evaluated for compositional bias using the SEG program [ 36].


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