Example sentences for: domain-containing

How can you use “domain-containing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The SH2 domain-containing inositol phosphatase (SHIP) downregulates Btk by dephosphorylating PIP3 [ 4, 5, 6].

  • We obtained multiple independent cDNA clones coding for BTBD1 and BTBD2, two uncharacterized, BTB domain-containing, kelch-like proteins.

  • PH-20 induces the expression of proapoptotic p53 [ 9 ] and WOX1 (WW domain-containing oxidoreductase; also known as WWOX or FOR) [ 10 ] , which contributes to the increased TNF cytotoxic effect.

  • These include linker for activation of T cells, T-cell-specific transcription factor 7, STAT4, IL-7R, PAS ser/thr kinase, l-mfa domain-containing protein, and an unknown gene designated DKFZp586D1122.

  • This GPCR-mediated regulation of ion channels also depends on the coordination and parallel regulation of protein tyrosine kinase and protein tyrosine phosphatase activities [ 24 ] . GPCRs can also interact with the growing family of PDZ domain-containing proteins [ 25 ] . All of these relationships are reflected in our study by the strong correlation between 7 transmembrane receptors (rhodopsin family) (PF00001), protein kinases (PF00069), protein tyrosine phosphatases (PF00102), ion transport proteins (PF00520), and PDZ domain proteins (PF00595).


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