Words similar to dna-rna

Example sentences for: dna-rna

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Earlier studies have shown that DAP, in DNA fragments, can widen the minor groove, as detected by reactivity towards uranyl nitrate or susceptibility to Dnase cleavage [ 29 ] , and can relieve compressions in the minor groove associated with A-tracts [ 30 ] . In contrast, NMR and molecular modeling studies of an oligonucleotide duplex containing MeC have demonstrated that, while this duplex still has a B-DNA conformation, there are differences in the structural parameters and thermal stability relative to the unmodified duplex [ 31 ] . An earlier study also found, in two closely related octanucleotide duplexes, that although the methylated duplexes retained their B-DNA conformation, different structural and thermal stability effects were seen [ 32 ] . Although these studies have been carried out with DNA-DNA and not DNA-RNA duplexes, it is possible that MeC substitution may have different structural consequences than DAP substitution.
Enhanced specificity against mismatches has also been observed by other groups when DAP is incorporated into PNA oligomers [ 13 ] and after C5-(1-propynyl)ation of pyrimidines in DNA-RNA duplexes [ 33 ] .
However, microarray hybridization result is consistent with DNA-RNA reassociation kinetic studies using multiple organs of tobacco plants [ 39].