Example sentences for: dna-based

How can you use “dna-based” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In each proband in whom a single A or B allele was detected by DNA-based typing, we verified the allele(s) and set phase to ascertain haplotypes of the proband using HFE and HLA analyses of appropriate family members.

  • Some probands were homozygous for A alleles by DNA-based typing and family studies: A*01 (n = 2), A*02 (n = 7), A*03 (n = 29), A*11 (n = 1), A*24 (n = 1), and A*24 (n = 1).

  • The FBN1 mutation detection rate for individuals with clinically diagnosed MFS is currently about 75% when the gene is completely screened with a DNA-based PCR amplification protocol of individual exons [ 15 26 ] . Genomic deletions such as the ones reported here are not a frequent cause of human disease and would be missed by this approach.

  • Finally, in the setting of specific B-cell clonal activation with concomitant clonal expansion, both the cDNA- and the DNA-based assays will indicate a dominant HCDR3 length.

  • An even more striking level of B-cell clonal dominance and expansion was seen when the genomic DNA-based assay was used to analyze B cells from the synovial fluid or synovial tissue (Figs 2and 3).


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