Words similar to dna-binding
Example sentences for: dna-binding
How can you use “dna-binding” in a sentence? Here are some example sentences to help you improve your vocabulary:
These architectures suggest that both the KilA-N and Bro-N modules are, to a large extent, functionally equivalent and probably act as the principal DNA-binding moiety that recruits a specific activity purveyed by their carboxy-terminal domains to the target DNA sequences.
All members of the HMG-box family possess a 70-80 amino acid DNA-binding domain (the HMG-box) related to a motif originally identified in HMGB1 [ 5 ] . The HMG-box may also be involved in protein-protein interactions.
It also has high affinity for binding to single-stranded DNA on its own when separated from the three tetracysteine motifs [ 36 ] . Based on the structural and DNA-binding properties of the E. coli topoisomerase I 14 kDa domain, one can conclude that it is possible for a subdomain in topoisomerase I to lose the Zn(II) binding cysteines during evolution and still maintains the Zn-ribbon structure and single-strand DNA binding properties [ 7 ] .
Extensive lineage-specific expansion and domain shuffling in DNA-binding regulators containing the KilA-N and Bro domains
This region can, by itself, activate transcription when targeted to the DNA via a heterologous DNA-binding domain [ 5 ] . On the other hand, the LRR plus C-terminal region of yCCR4 cannot mediate transcription activation, but is involved in protein-protein interactions [ 5 ] . The yCCR4 LRR is necessary for the binding of several components of the CCR4-NOT complex, including yPOP2 -and mCAF1- [ 11 ] , yDBF2 [ 2 ] , yCAF4 and yCAF16 [ 8 ] , and deletion of the yCCR4 N-terminus does not impair these associations.
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