Words similar to dna-pk
Example sentences for: dna-pk
How can you use “dna-pk” in a sentence? Here are some example sentences to help you improve your vocabulary:
Similarly, mutation of serine 37, which abolishes the DNA-PK phosphorylation site, blocks phosphorylation of p53 by GSK3β.
DNA-PK is 460 kd DNA-activated protein kinase which participates in the cellular response to DNA damage [ 41].
The GSK3β phosphorylation site was identified by mutagenesis as serine 33 of p53, and we were able to show that this was dependent on prior phosphorylation of serine 37 by DNA-PK.
Whether DNA-PK is required for p53 activation in response to other stimuli is not known.
DNA-PK is involved in DNA strand-break repair, and can phosphorylate serines 15 and serine 37 of p53 in vitro [ 32].