Example sentences for: disulfide

How can you use “disulfide” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Presumably, reduction of the disulfide restores the binding of zinc and its inhibitory association with the sigma factor.

  • For example, exon-skipping mutations in the central region of the gene, exons 24-32, cause severe phenotypes or neonatal presentations [ 8 ] . But there are exceptions, only four of the many other mutations in this region cause severe phenotypes, while one mutation predicted to lead to skipping of exon 24 was found in a patient with classic MFS [ 5 ] . In contrast, most cysteine substitutions cause classic MFS with a high frequency of lens dislocation, although some patients in our study did not meet the Ghent criteria for diagnosis of MFS [ 9 ] . Amino-acid substitutions not disrupting disulfide bonds may be associated with fibrillinopathies other than MFS, although mutations in the calcium-binding consensus sequence have been reported in individuals with classic MFS [ 5 10 11 12 ] . It is clear from the studies reported so far, that genotype-phenotype correlations are not straight-forward for FBN1 mutations.

  • For dual localization experiments, a 1:1000 dilution of a rabbit polyclonal anti-β-coatomer protein (β-COP) antibody (Affinity BioReagents) or a 1:200 dilution of a rabbit polyclonal anti-protein disulfide isomerase (PDI) antibody (StressGen Biotechnologies) was included with the EE mouse monoclonal.

  • Buthoid venom has been reported to strongly affect a wide variety of vertebrate and invertebrate organisms [ 4 ] and its toxicity is attributed to the presence of a large variety of basic polypeptides cross-linked by 3-4 disulfide bridges [ 1 4 ] . Based on their molecular size and pharmacological activity, these toxins are classified into two main groups.

  • In the case of proteins that have a nearby cysteinyl residue, a disulfide bond forms between the two sulfur atoms.


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