Example sentences for: disulfide

How can you use “disulfide” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The sulfenated cysteinyl residue also can react with a cysteinyl residue on another protein or with glutathione, leading to a mixed disulfide.

  • Capture probes were synthesized using an alkane chain of 16 residues terminated at the 3'-end with a disulfide which was spotted onto the gold electrode on the chips to form a self-assembled monolayer [ 10 ] . The chips were glued into a plastic housing with a port for sample introduction.

  • contains three glutaredoxins that utilize the reducing power of glutathione to catalyze the reduction of disulfide bonds (–S–S–) in the presence of NADPH and glutathione reductase.

  • The first, the ER overload response, triggers the activation of the transcription factor NFkB and the subsequent upregulation of inflammatory proteins [ 13 ] . The second, the unfolded protein response (UPR) induces three divergent cellular events: (i) the activation of transcription factor ATF6 leading to the upregulation of ER chaperones such as protein disulfide isomerase, (ii) upregulation of the pro-apoptotic transcription factor GADD153 and (iii) suppression of protein synthesis via phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) by pancreatic eIF2α kinase (PEK/PERK, [ 11 12 ] ). Upregulation of the ER chaperones, GADD153 and PERK in response to a toxic insult would constitute direct evidence of an ER stress response.

  • A disulfide bridge (the so-called cys-loop), present only in the alpha subunits of nAChR, is known to be part of the agonist binding site of the receptor [ 7 ] . This was a clear indication that, in order to build a dimer interface that includes the ligand binding pocket, alpha subunits had to be aligned onto the template monomer presenting a disulfide bridge at the interface (subunit 1).


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