Words similar to disulfide
Example sentences for: disulfide
How can you use “disulfide” in a sentence? Here are some example sentences to help you improve your vocabulary:
The first, the ER overload response, triggers the activation of the transcription factor NFkB and the subsequent upregulation of inflammatory proteins [ 13 ] . The second, the unfolded protein response (UPR) induces three divergent cellular events: (i) the activation of transcription factor ATF6 leading to the upregulation of ER chaperones such as protein disulfide isomerase, (ii) upregulation of the pro-apoptotic transcription factor GADD153 and (iii) suppression of protein synthesis via phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) by pancreatic eIF2α kinase (PEK/PERK, [ 11 12 ] ). Upregulation of the ER chaperones, GADD153 and PERK in response to a toxic insult would constitute direct evidence of an ER stress response.
For dual localization experiments, a 1:1000 dilution of a rabbit polyclonal anti-β-coatomer protein (β-COP) antibody (Affinity BioReagents) or a 1:200 dilution of a rabbit polyclonal anti-protein disulfide isomerase (PDI) antibody (StressGen Biotechnologies) was included with the EE mouse monoclonal.
Almost all cell types express TGF-β, but the highest level of expression of TGF-β is in platelets and bone [ 3 ] . Mature TGF-β1 consists of two identical peptide chains, each containing 112 amino acids, linked via nine disulfide bonds [ 4 ] . TGF-β1 is synthesized as part of a large, latent protein complex, unable to bind to cellular receptors, with mature active TGF-β1 produced by cleavage [ 5 ] .
The first group contains short toxins (30-40 amino acid residues) with 3-4 disulfide bridges which mainly affect the voltage dependent K +channels and the large conductance calcium activated K +channels [ 5 6 ] . The second group includes long-chain (60-70 amino acids) peptides cross linked by 4 disulfide bridges which mainly have an effect on voltage dependent sodium channels of excitable cells [ 1 2 ] . According to their species selectivity sodium channel toxins have been divided into mammalian and insect toxins.
Unlike arginine, cysteine can participate in disulfide bridge formation and thus has the potential to produce a marked difference in the functional activity of 5α-reductase 1 in B6 compared to D2 animals.
Loading...