Example sentences for: disulfide

How can you use “disulfide” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The sulfenated cysteinyl residue also can react with a cysteinyl residue on another protein or with glutathione, leading to a mixed disulfide.

  • There is direct and circumstantial evidence that the residues form an intra-or inter-molecular disulfide bond in many G-protein-coupled receptors, and in some cases these are critical for their ligand recognition and membrane trafficking [ 48, 49, 50].

  • As mentioned above, proteins—in particular, the thiols of cysteines—are the major targets of H 2 O 2 . The reaction of cysteinyl thiolates with H 2 O 2 can lead to the formation of different modifications, such as sulfenic acid (–SOH), sulfinic acid (–SO 2 H), and sulfonic acid (–SO3H), as well as disulfide bond formation (–S–S–) and glutathione conjugation (–S–GSH) (Jacob et al.

  • Given the reversibility of thiol oxidations and the wide range of structural constraints that can be imposed by the formation of a sulfenic or sulfinic acid or a disulfide bond, we predict there will be many more examples of regulation by thiol modification.

  • We selected it for this study because it is rapidly bactericidal, functions well at elevated physiological salt concentrations such as those that may occur in the CF lung, and has a broad spectrum of activity [ 21 22 23 ] . PG-1's antiparallel β-hairpin structure and antimicrobial activity in physiological and elevated salt concentrations are maintained by its two intramolecular cystine disulfide bonds [ 21 24 25 26 27 28 ] . The antimicrobial spectrum of PG-1 includes Chlamydia trachomatis , Candida albicans , Escherichia coli , Fusobacterium nucleatum, Haemophilus ducreyi , Listeria monocytogenes , Neisseria gonorrhoeae , Porphyromonas gingivalis , Prevotella intermedia , P. aeruginosa , and Staphylococcus aureus [ 20 22 25 29 30 31 32 ] .


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