Words similar to disease-causative
Example sentences for: disease-causative
How can you use “disease-causative” in a sentence? Here are some example sentences to help you improve your vocabulary:
As we found no likely disease-causative mutations in our first pass DHPLC conditions, we sequenced all four patients exons 56-78 and the 7 fragments of the 3'-UTR (the first of which contains exon 79).
When a likely disease-causative mutation was found in each of these patients, no further fragments were sequenced for that patient.
Two of the patients in which we found disease-causative mutations have affected brothers, three in addition to patient 01, have potential carrier sisters, and all six have mothers who could also be carriers.
In total, likely disease-causative mutations were found in six of the eight male patients and confirmed in the carrier sister (patient 01s) of one of the six patients (patient 01).
Patient 01 and his carrier sister were shown to have a C->T substitution in exon 39 bp5762, predicting a nonsense mutation Gln->Stop, leading to a likely disease-causative truncation of the protein (Table 2and Figure 1).