Example sentences for: disease-causative

How can you use “disease-causative” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As we found no likely disease-causative mutations in our first pass DHPLC conditions, we sequenced all four patients exons 56-78 and the 7 fragments of the 3'-UTR (the first of which contains exon 79).

  • In two patients, 05 and 06, we did not find likely disease-causative mutations despite sequencing all 86 fragments.

  • Patient 01 and his carrier sister were shown to have a C->T substitution in exon 39 bp5762, predicting a nonsense mutation Gln->Stop, leading to a likely disease-causative truncation of the protein (Table 2and Figure 1).

  • The second is a probable novel disease-causative mutation, 10015+5 G->A in intron 67, within the splice site consensus sequence in patient 08.

  • When a likely disease-causative mutation was found in each of these patients, no further fragments were sequenced for that patient.


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