Example sentences for: disease-causative

How can you use “disease-causative” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Patient 01 and his carrier sister were shown to have a C->T substitution in exon 39 bp5762, predicting a nonsense mutation Gln->Stop, leading to a likely disease-causative truncation of the protein (Table 2and Figure 1).

  • Details of the reagent costs per patient calculations are attached as Additional file A. Briefly, we assumed that likely disease-causative mutations would be found, on average, within approximately 43 fragments.

  • The second is a probable novel disease-causative mutation, 10015+5 G->A in intron 67, within the splice site consensus sequence in patient 08.

  • In total, likely disease-causative mutations were found in six of the eight male patients and confirmed in the carrier sister (patient 01s) of one of the six patients (patient 01).

  • As we found no likely disease-causative mutations in our first pass DHPLC conditions, we sequenced all four patients exons 56-78 and the 7 fragments of the 3'-UTR (the first of which contains exon 79).


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