Words similar to disease-causative
Example sentences for: disease-causative
How can you use “disease-causative” in a sentence? Here are some example sentences to help you improve your vocabulary:
In total, likely disease-causative mutations were found in six of the eight male patients and confirmed in the carrier sister (patient 01s) of one of the six patients (patient 01).
Patient 07 has a C->T substitution in exon 23 at bp 3359 predicting a nonsense mutation Arg->Stop, leading to a likely disease-causative truncation of the protein.
Two of the patients in which we found disease-causative mutations have affected brothers, three in addition to patient 01, have potential carrier sisters, and all six have mothers who could also be carriers.
Patient 01 and his carrier sister were shown to have a C->T substitution in exon 39 bp5762, predicting a nonsense mutation Gln->Stop, leading to a likely disease-causative truncation of the protein (Table 2and Figure 1).
Details of the reagent costs per patient calculations are attached as Additional file A. Briefly, we assumed that likely disease-causative mutations would be found, on average, within approximately 43 fragments.