Words similar to disease-causative
Example sentences for: disease-causative
How can you use “disease-causative” in a sentence? Here are some example sentences to help you improve your vocabulary:
When a likely disease-causative mutation was found in each of these patients, no further fragments were sequenced for that patient.
As we found no likely disease-causative mutations in our first pass DHPLC conditions, we sequenced all four patients exons 56-78 and the 7 fragments of the 3'-UTR (the first of which contains exon 79).
Two of the patients in which we found disease-causative mutations have affected brothers, three in addition to patient 01, have potential carrier sisters, and all six have mothers who could also be carriers.
Details of the reagent costs per patient calculations are attached as Additional file A. Briefly, we assumed that likely disease-causative mutations would be found, on average, within approximately 43 fragments.
Patient 01 and his carrier sister were shown to have a C->T substitution in exon 39 bp5762, predicting a nonsense mutation Gln->Stop, leading to a likely disease-causative truncation of the protein (Table 2and Figure 1).