Example sentences for: disease-causative

How can you use “disease-causative” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In total, likely disease-causative mutations were found in six of the eight male patients and confirmed in the carrier sister (patient 01s) of one of the six patients (patient 01).

  • Two of the patients in which we found disease-causative mutations have affected brothers, three in addition to patient 01, have potential carrier sisters, and all six have mothers who could also be carriers.

  • Patient 07 has a C->T substitution in exon 23 at bp 3359 predicting a nonsense mutation Arg->Stop, leading to a likely disease-causative truncation of the protein.

  • The second is a probable novel disease-causative mutation, 10015+5 G->A in intron 67, within the splice site consensus sequence in patient 08.

  • When a likely disease-causative mutation was found in each of these patients, no further fragments were sequenced for that patient.


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