Example sentences for: disease-modifying

How can you use “disease-modifying” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although initial detection of a disease association in TNF may be difficult, weak allelic associations within the TNF gene region will make it possible to distinguish a disease-modifying SNP from its neighbors.

  • All patients had to have had at least one failed trial of a disease-modifying antirheumatic drug (DMARD) and had to have at least 10 painful and 10 swollen joints at entry.

  • ACR = American College of Rheumatology; CRP = C-reactive protein; DMARD = disease-modifying antirheumatic drug; IL = interleukin; NF = nuclear factor; RA = rheumatoid arthritis; rhIL-11 = recombinant human IL-11; TNF = tumor necrosis factor.

  • Etanercept (sTNFR:Fc) and infliximab (chimeric anti-TNF monoclonal antibody) have been shown to be efficacious in the treatment of patients with RA for whom treatment with at least one disease-modifying antirheumatic drug had previously failed [ 11, 12]; both of these biologicals have been approved by regulatory agencies for the treatment of patients with RA.

  • Still, if the reported disease-modifying effect of atorvastatin is confirmed in the National Institute on Aging's large, multi-center trial of simvastatin, one or more compounds of this class may be among the first disease-modifying compounds approved by the Food and Drug Administration for slowing the progression of Alzheimer disease.


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