Example sentences for: disease-modifying

How can you use “disease-modifying” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Etanercept (sTNFR:Fc) and infliximab (chimeric anti-TNF monoclonal antibody) have been shown to be efficacious in the treatment of patients with RA for whom treatment with at least one disease-modifying antirheumatic drug had previously failed [ 11, 12]; both of these biologicals have been approved by regulatory agencies for the treatment of patients with RA.

  • Although initial detection of a disease association in TNF may be difficult, weak allelic associations within the TNF gene region will make it possible to distinguish a disease-modifying SNP from its neighbors.

  • Currently the symptoms of arthritis are managed using pharmacologic agents, including both steroidal and nonsteroidal drugs, and disease-modifying drugs such as methotrexate.

  • The clinical features of the 66 patients studied are shown in Table 1. Patients with RA were older, had more tender and swollen joints, were rheumatoid factor positive, and were more likely to be on disease-modifying antirheumatic drug therapy than were non-RA patients.

  • All patients had to have had at least one failed trial of a disease-modifying antirheumatic drug (DMARD) and had to have at least 10 painful and 10 swollen joints at entry.


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