Words similar to disease-associated
Example sentences for: disease-associated
How can you use “disease-associated” in a sentence? Here are some example sentences to help you improve your vocabulary:
The finding that disease-associated mutations occur in positions of functional importance supports recent efforts for the building of methods to predict which positions are likely to be disease associated [ 14 13 16 17 ] . These methods are likely to incorporate protein structure, the amino acid identity of the mutation and phylogenetic information.
Further studies are needed to identify patients at higher risk of severe LH infection to prevent disease-associated morbidity and to test the hypothesis that HHV-6 infection early in the infancy may be protective against leukemia in the frame of Greaves hypothesis.
Reported mutations often occur in the highly conserved alpha-helix-initiation motif of rod domain 1A or in the alpha-helix-termination motif of rod domain 2B [ 19 ] . Structure based analysis methods have also been used to analyze Osteogenesis imperfecta associated COL1A1 mutations and disease-associated P53 mutations (Mooney and Klein, unpublished), [ 20 ] . Miller and Kumar have reported that disease-associated mutations are conserved in seven model genes [ 21 ] .
The results show that, in general, positions with disease-associated mutations are conserved more than the average position in the alignment.
While it has been shown in specific cases that disease-associated amino acid substitutions affect protein function, until now few studies have examined this across many genes.