Words similar to disease-associated
Example sentences for: disease-associated
How can you use “disease-associated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our method compares the negative entropy of disease-associated columns within an alignment to other columns in that alignment.
An analysis of the breast and ovarian cancer susceptibility gene, BRCA1, showed that disease-associated mutations tend to occur in highly conserved regions [ 18 ] . An analysis of homologous sequences in the androgen receptor has shown similar results [ 10 ] . Keratin 12, KRT12, is associated with Meesmann Corneal Epithelial Dystrophy (MCD).
Reported mutations often occur in the highly conserved alpha-helix-initiation motif of rod domain 1A or in the alpha-helix-termination motif of rod domain 2B [ 19 ] . Structure based analysis methods have also been used to analyze Osteogenesis imperfecta associated COL1A1 mutations and disease-associated P53 mutations (Mooney and Klein, unpublished), [ 20 ] . Miller and Kumar have reported that disease-associated mutations are conserved in seven model genes [ 21 ] .
Here we provide direct evidence that disease-associated point mutations occur in functionally important regions of the genome and are not distributed equally across the coding regions of genes.
They were chosen because they had a reported cDNA sequence, disease-associated mutations and homologs in SWISSPROT.
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