Words similar to disease-associated
Example sentences for: disease-associated
How can you use “disease-associated” in a sentence? Here are some example sentences to help you improve your vocabulary:
The goal of this work is to build these alignments, map the mutations to them, and show that disease-associated positions are, in general, conserved.
While it has been shown in specific cases that disease-associated amino acid substitutions affect protein function, until now few studies have examined this across many genes.
Here we provide direct evidence that disease-associated point mutations occur in functionally important regions of the genome and are not distributed equally across the coding regions of genes.
An analysis of the breast and ovarian cancer susceptibility gene, BRCA1, showed that disease-associated mutations tend to occur in highly conserved regions [ 18 ] . An analysis of homologous sequences in the androgen receptor has shown similar results [ 10 ] . Keratin 12, KRT12, is associated with Meesmann Corneal Epithelial Dystrophy (MCD).
These multiple alignments have then been used to assess the difference in evolutionary conservation for positions that are both disease-associated and not associated.