Example sentences for: disease-associated

How can you use “disease-associated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • An analysis of the breast and ovarian cancer susceptibility gene, BRCA1, showed that disease-associated mutations tend to occur in highly conserved regions [ 18 ] . An analysis of homologous sequences in the androgen receptor has shown similar results [ 10 ] . Keratin 12, KRT12, is associated with Meesmann Corneal Epithelial Dystrophy (MCD).

  • To determine the degree to which mutation positions differ evolutionarily from other positions, we have built alignments of homologous genes for 231 disease-associated genes.

  • While it has been shown in specific cases that disease-associated amino acid substitutions affect protein function, until now few studies have examined this across many genes.

  • A naturally occuring Asn57Asp polymorphism may be associated with JOAG [ 39 ] which, if truly disease-associated, would suggest the functional importance of N-linked glycosylation.

  • The goal of this work is to build these alignments, map the mutations to them, and show that disease-associated positions are, in general, conserved.


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