Words similar to disease-associated
Example sentences for: disease-associated
How can you use “disease-associated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Here we provide direct evidence that disease-associated point mutations occur in functionally important regions of the genome and are not distributed equally across the coding regions of genes.
The results show that, in general, positions with disease-associated mutations are conserved more than the average position in the alignment.
An analysis of the breast and ovarian cancer susceptibility gene, BRCA1, showed that disease-associated mutations tend to occur in highly conserved regions [ 18 ] . An analysis of homologous sequences in the androgen receptor has shown similar results [ 10 ] . Keratin 12, KRT12, is associated with Meesmann Corneal Epithelial Dystrophy (MCD).
To determine the degree to which mutation positions differ evolutionarily from other positions, we have built alignments of homologous genes for 231 disease-associated genes.
While it has been shown in specific cases that disease-associated amino acid substitutions affect protein function, until now few studies have examined this across many genes.
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