Words similar to dihydrotestosterone
Example sentences for: dihydrotestosterone
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We tested the responses of normal and AIS genital fibroblasts to dihydrotestosterone (DHT), under culture conditions similar to those that were reported to produce aromatase induction in these cells [ 8 ] . Cells were treated with DHT (100-1,000 nM) both at confluency (G 0 ) and during exponential growth, and transcript levels were assessed using DNA microarrays.
In the first, LNCaP cells were treated for 24 hours with dihydrotestosterone (DHT), the predominant androgen found in the prostate in vivo.
With every media exchange every 48 h, cells received either ethanol in a final dilution of 1:100,000 or 100 nM dihydrotestosterone (DHT) dissolved in ethanol.
Although two previous reports have shown increases in aromatase enzymatic activity in genital skin fibroblasts treated with dihydrotestosterone (DHT) [ 8 27 ] , others have failed to observe changes in aromatase activity in response to androgen [ 28 ] . In agreement with our findings, Elmlinger
In 1981, Griffin et al [ 29 ] reported variation in the activity of steroid 5alpha reductase, the enzyme that converts testosterone to dihydrotestosterone, in cloned human skin fibroblasts.