Example sentences for: dihydrotestosterone

How can you use “dihydrotestosterone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In 1981, Griffin et al [ 29 ] reported variation in the activity of steroid 5alpha reductase, the enzyme that converts testosterone to dihydrotestosterone, in cloned human skin fibroblasts.

  • Although two previous reports have shown increases in aromatase enzymatic activity in genital skin fibroblasts treated with dihydrotestosterone (DHT) [ 8 27 ] , others have failed to observe changes in aromatase activity in response to androgen [ 28 ] . In agreement with our findings, Elmlinger

  • Several mechanisms could be involved in this AR activation [ 21 22 23 ] . Changes in the specificity of AR broadening the responsive spectrum to other steroid hormones different to dihydrotestosterone, can be caused by genetic mutations affecting different regions of AR.

  • In the first, LNCaP cells were treated for 24 hours with dihydrotestosterone (DHT), the predominant androgen found in the prostate in vivo.

  • Similar finding were previously obtained with the synthetic androgen R1881 and the natural androgen dihydrotestosterone (DHT) [ 42 43 ] . The latter study also showed that p27 is quantitatively bound to cyclin E complexes in DHT-treated cells, indicating that p27 upregulation was sufficient to saturate and inhibit cyclinE/CDK2 complexes [ 43 ] .


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