Words similar to dihydrotestosterone
Example sentences for: dihydrotestosterone
How can you use “dihydrotestosterone” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although two previous reports have shown increases in aromatase enzymatic activity in genital skin fibroblasts treated with dihydrotestosterone (DHT) [ 8 27 ] , others have failed to observe changes in aromatase activity in response to androgen [ 28 ] . In agreement with our findings, Elmlinger
Androgen binding protein (ABP) is produced by Sertoli cells of the testis, secreted into the lumen of seminiferous tubules, and transported with tubular fluid to the epididymis, where it is internalized and degraded by the epithelial cells of the initial segment and the caput; it binds testosterone (T), dihydrotestosterone and estradiol with high affinity [ 9 10 11 ] . The functions of ABP have been the subject of many reviews [e.g.
Several mechanisms could be involved in this AR activation [ 21 22 23 ] . Changes in the specificity of AR broadening the responsive spectrum to other steroid hormones different to dihydrotestosterone, can be caused by genetic mutations affecting different regions of AR.
In 1981, Griffin et al [ 29 ] reported variation in the activity of steroid 5alpha reductase, the enzyme that converts testosterone to dihydrotestosterone, in cloned human skin fibroblasts.
We tested the responses of normal and AIS genital fibroblasts to dihydrotestosterone (DHT), under culture conditions similar to those that were reported to produce aromatase induction in these cells [ 8 ] . Cells were treated with DHT (100-1,000 nM) both at confluency (G 0 ) and during exponential growth, and transcript levels were assessed using DNA microarrays.
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