Words similar to dihydroxyvitamin

Example sentences for: dihydroxyvitamin

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In these studies there was a significant increase in CaT1 mRNA levels at the lowest dose (10 -9mol/L) of 1,25-dihydroxyvitamin D studied (Figure 4), while a slightly higher level of CaT1 mRNA expression was observed at 10 -8mol/L 1,25-dihydroxyvitamin D, no further effect on CaT1 mRNA was seen with another 10-fold increase in 1,25-dihydroxyvitamin D concentration.
Calcium extrusion at the basolateral membrane is an active process involving a Ca-ATPase that may also be affected by vitamin D status [ 8 ] . However, although it has been known for more than 20 years that the rate of Ca transport across the intestinal brush border membrane can be increased by 1,25-dihydroxyvitamin D [ 9 ] , the identity of the calcium transport protein involved in Ca influx has not been ascertained.
If CaT1 is an important regulator of intestinal calcium absorption, it is likely that it would be regulated by 1,25-dihydroxyvitamin D. As shown in Figure 2, treatment of cells for 24 h with 10 -7mol/L 1,25-dihydroxyvitamin D caused a 10-fold increase (p < 0.001, ANOVA, n= 10 studies) in CaT1 mRNA expression.
The relationship between the dose of 1,25-dihydroxyvitamin D treatment and CaT1 mRNA response was investigated in a third set (n= 3 studies) of experiments at 10 -9, 10 -8, and 10 -7mol/L 1,25-dihydroxyvitamin D for 24 h.
CaT1 and ECaC1 are found in several tissues, including 1,25-dihydroxyvitamin D-responsive epithelia in the intestine and kidney.