Example sentences for: dihydroxyvitamin

How can you use “dihydroxyvitamin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As shown in Figure 3, the response of CaT1 mRNA to 1,25-dihydroxyvitamin D is rapid (n = 6 studies).

  • In time-course studies, cells were treated with 100 nanomol/L 1,25-dihydroxyvitamin D diluted in DMEM + 5% FBS for 0, 2 h, 4 h, 8 h and 24 h.

  • This cell line spontaneously differentiates in culture and expresses biochemical and morphological characteristics of well-differentiated small intestine-like enterocytes [ 17 23 ] . We have previously shown that Caco-2 cells possess a classical nuclear vitamin D receptor [ 18 ] that directly mediates vitamin D-dependent gene expression [ 22 ] , and exhibits a high degree of specificity for various vitamin D metabolites and analogs [ 20 21 ] . Most importantly, in response to short-term (<24 h) 1,25-dihydroxyvitamin D treatment, Caco-2 cells increase transepithelial calcium transport [ 17 ] and calbindin D 9K expression [ 19 ] , a cytosolic calcium binding protein.

  • 1,25-dihydroxyvitamin D causes a rapid and marked up regulation of CaT1 expression

  • However, such association studies will not completely settle the question of the relative importance of either of these vitamin D-induced genes in the calcium transport response to 1,25-dihydroxyvitamin D. Those questions will be likely answered more directly in the future by individually altering the expression of these calcium transport genes in transfected cell lines or in transgenic animal models.


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