Example sentences for: dihydropteroate

How can you use “dihydropteroate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Several well-characterized plasmodial genes were identified in this metabolic collection, including P. falciparum lactate dehydrogenase (PfLDH; 027743), enolase (U00152), triose-phosphate isomerase (PfTPI; L01654), glucose-6-phosphate isomerase (PfG6PI; J05544), hypoxanthine-guanine phosphoribosyl-transferase (PfHGPRT; X16279) and dihydropteroate synthetase (PfDHPS; U07706).

  • Dihydropteroate synthase (DHPS) catalyzes the condensation of p -aminobenzoic acid with 7,8-dihydro-6-hydroxymethylpterin pyrophosphate to give 7,8-dihydropteroate, an intermediate in folate metabolism.

  • A case in point is the MJ0107 protein, the apparent archaeal ortholog of DHPS, which failed to show dihydropteroate synthase activity [ 25].

  • It was acknowledged that MJ0107 (a member of COG0294) could be identified as a possible homolog of DHPS by sequence-based methods, and this protein was assayed for dihydropteroate synthase activity, but none was detected [ 25].

  • In contrast, most of the MJ0301 residues described as equivalent to the functionally important residues of Escherichia coli dihydropteroate synthase are not conserved, even among the archaeal orthologs of this protein.


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