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Example sentences for: dids
How can you use “dids” in a sentence? Here are some example sentences to help you improve your vocabulary:
The observed effects of Cl -channel antagonists differ significantly between the present study where DIDS prevented 4-AP from decreasing progesterone synthesis and previous investigations where DIDS and other Cl -channel antagonists prevented LH from enhancing progesterone production [ 29 35 56 ] . However, this discrepancy is expected, because DIDS antagonizes a chloride influx pathway in pig GC, and chloride efflux pathways in Leydig cells.
Membrane potential was further depolarized in GC exposed to 4-AP in the presence of DIDS (Figure 8B), consistent with the hypothesis that 4-AP-induced hyperpolarization depends on chloride influx.
4-aminopyridine (4-AP); analysis of variance (ANOVA); 8-(4-chlorophenylthio)adenosine-3',5'-cyclic monophosphorothioate (8-CPT-cAMP); 4',4' diisothicyanato-stilbene-2-2'-disulfonic acid (DIDS); bis-(1,3-dibutylbarbituric acid)trimethine oxonol (DiBAC 4 (3)); 5α-dihydrotestosterone (5α-DHT); Dulbecco's modified eagle's medium (DMEM); enhanced chemiluminescence (ECL); ethylenediaminetetraacetic acid (EDTA); fetal bovine serum (FBS); follicle stimulating hormone (FSH); granulosa cells (GC); human chorionic gonadotropin (hCG); 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid (HEPES); 3β-hydroxysteroid dehydrogenase (3β-HSD); 3-isobutyl-1-methylxanthine (IBMX); least significant difference (LSD); luteinizing hormone (LH); mitogen activated protein kinase (MAPK); 1,3-Benzenedicarboxylic acid, 4,4'-[1,4,10,13-tetraoxa-7,16-diazacyclooctadecane-7,16-diylbis(5-methoxy-6,2-benzofurandiyl)]bis-, tetrakis [(acetyloxy)methyl] ester (PBFI-AM); phosphate-buffered saline (PBS); proliferating cell nuclear antigen (PCNA); protein kinase A (PKA); sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE); steroidogenic acute regulatory protein (StAR); tris-buffered saline (TBS).
Exposure to DIDS alone significantly decreased (depolarized) GC resting membrane potential (Figure 8B), suggesting that an outward chloride current (chloride influx) contributes to the normal resting potential of pig GC.
To test this hypothesis, the effects of 4-AP on membrane potential were examined using GC incubated in either media modified to contain the chloride channel antagonist DIDS, or a physiological buffer solution modified to contain a low (8 mM) concentration of chloride.
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