Example sentences for: diaphragmatic

How can you use “diaphragmatic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is possible that in emphysema, the additional impact on diaphragmatic physiology of fiber shortening resulting from pulmonary hyperexpansion [ 1 2 3 4 5 6 ] affects MHC isoform shifts beyond the influence of a pure increase in the workload on the muscle.

  • Other studies of MHC adaptation in animal models of increased diaphragmatic work have had conflicting results.

  • Other factors that might lead to less impressive MHC shifts in rodent models of emphysema than in humans include the much shorter time course over which the adaptations have a chance to occur, the greater compliance of the rodent thorax to pulmonary hyperexpansion, and differences in the diaphragmatic load created in the human disease in comparison with the animal models that have yet to be fully worked out.

  • In sum, we have demonstrated a significant decrease in IIb MHC expression at both the protein and mRNA levels in the diaphragmatic muscle of rats with elastase-induced emphysema.

  • In addition to being the first demonstration of a decrease in the expression of the IIb MHC isoform in an animal model of emphysema, this study is the first to demonstrate that such a shift toward slower isoforms in emphysema has a significant physiologic impact on diaphragmatic function in vitro . We show that both twitch speed and fatiguing properties move toward slower-twitch characteristics with this decrease in IIb expression.


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