Example sentences for: dexfenfluramine

How can you use “dexfenfluramine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This week, the FDA reported 58 new cases of abnormal heart valves in patients on fen-phen, and the Journal of the American Medical Association reported animal evidence linking both dexfenfluramine and fenfluramine to toxic brain effects.

  • We first sought to identify all published studies with echocardiographic assessment of cardiac valve regurgitation in persons exposed to fenfluramine or dexfenfluramine and in suitable controls.

  • In conclusion, we have estimated risks associated with use of fenfluramine or dexfenfluramine for developing FDA-positive AR and MR after correcting for two major sources of bias.

  • Indeed, the most recently published study (which did not suffer from measurement bias) showed a high prevalence (30%) of AR in persons taking fenfluramine or dexfenfluramine at the time of the echocardiogram, similar to the older prevalence studies [ 15 ] . Regarding the potential reversibility of valve dysfunction, great caution must be exercised in assuming any substantial reversal of valvular plaques, as recent pathological studies suggest a progressive nature to these lesions [ 33 ] . Furthermore, limited, early apparent echocardiographic improvement of acute rheumatic carditis has also been recently demonstrated [ 34 ] . The early improvement seen in this setting certainly does not preclude later progression of rheumatic valvular heart disease.

  • Dr. Hopkins and Dr. Polukoff have been retained as consultants for plaintiff attorneys representing persons who have taken fenfluramine and dexfenfluramine.


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