Words similar to dexfenfluramine
Example sentences for: dexfenfluramine
How can you use “dexfenfluramine” in a sentence? Here are some example sentences to help you improve your vocabulary:
In conclusion, we have estimated risks associated with use of fenfluramine or dexfenfluramine for developing FDA-positive AR and MR after correcting for two major sources of bias.
There were differences in study design and methods (though most were quite similar), fenfluramine or dexfenfluramine doses (though in most studies, doses were similar), additional drugs used, patient characteristics, interval between cessation of therapy and echocardiography, and completeness of follow-up.
These findings lend strong support to the view that fenfluramine and dexfenfluramine are potent causal factors in the development of both aortic and mitral valvular heart disease.
The search for studies included examination of prior meta-analyses and reviews, MEDLINE search (using the terms fenfluramine or dexfenfluramine, diet drugs, echocardiogram or echocardiographic, and valvular heart disease), and review of references of identified articles.
Indeed, the most recently published study (which did not suffer from measurement bias) showed a high prevalence (30%) of AR in persons taking fenfluramine or dexfenfluramine at the time of the echocardiogram, similar to the older prevalence studies [ 15 ] . Regarding the potential reversibility of valve dysfunction, great caution must be exercised in assuming any substantial reversal of valvular plaques, as recent pathological studies suggest a progressive nature to these lesions [ 33 ] . Furthermore, limited, early apparent echocardiographic improvement of acute rheumatic carditis has also been recently demonstrated [ 34 ] . The early improvement seen in this setting certainly does not preclude later progression of rheumatic valvular heart disease.
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