Example sentences for: dexamethasone

How can you use “dexamethasone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • hESMPCs were plated at low density (1 × 10 3 to 2.5 × 10 3 cells/cm 2 ) on tissue-culture-treated dishes in the presence of 10 mM β-glycerol phosphate (Sigma), 0.1 μM dexamethasone, and 200 μM ascorbic acid in alpha MEM medium containing 10% FBS for 3–4 wk.

  • Several lines of evidence indicate that NF-κB is constitutively activated in cancer cells, suggesting that it plays an important role in tumorigenesis [ 30 ] . Activated glucocorticoid receptors have been shown to repress NF-κB-mediated gene expression [ 31 ] , and to cause a significant reduction in nuclear levels of p65 protein, a subunit of NF-κB [ 31 ] . A variety of mitogens, cytokines, and reactive oxygen intermediates have been shown to rapidly cause the translocation of NF-κB to the nucleus [ 30 31 32 ] , and the ability of dexamethasone to interfere with this translocation is blocked by prior treatment with the glucocorticoid antagonist RU 486 [ 30 ] . Based on these findings, it is plausible to speculate that exposure to RU 486 may interfere with the function of endogenous glucocorticoids as regulators of cell cycle, allowing the initiation and progression of malignant transformation of liver cells.

  • 3%), dexamethasone (0.

  • Moreover, we found that while both cell lines synthesized IL-6 constitutively, only the IL-6 production of NRP-152 cells was inhibited by dexamethasone treatment (Figure 5).

  • We found that dexamethasone treatment of NRP-152 cells inhibited IL-6 synthesis without affecting cell growth.


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