Example sentences for: dexamethasone

How can you use “dexamethasone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The mouse homologue of one of the candidate biomarkers, LNC2, has been shown to be regulated at the transcriptional level by dexamethasone in murine cells [ 22 ] . However, there is no published evidence that the human LCN2 gene is likewise dexamethasone-inducible, and there is no description of glucocorticoid-responsive elements in the 5' regulatory region of the human LCN2 gene [ 28 ] . Further, preliminary investigation in our laboratory, using in vitro cultures of purified PBMCs from healthy volunteers, indicates that neither the LCN2 gene nor any of the other 3 transcripts is directly inducible by acute treatment with either SU5416 or dexamethasone (data not shown).

  • cDNA - DNA complementary to ribonucleic acid (RNA), DNA - deoxyribonucleic acid, PBS - phosphate buffer saline, DEX - dexamethasone, EST - expressed sequence tag, SAGE - serial analysis of gene expression, SCA - single clone analysis, MA - mixed analysis, bp - base pairs, StDev - Standard Deviation, RT-PCR - real-time polymerase chain reaction.

  • To examine the role of autocrine IL-6 on NRP-152 and NRP-154 cells, we looked at the effect of dexamethasone treatment on IL-6 expression on both cell lines, and on high and low IL-6-expressing clones of NRP-154 cells.

  • Dexamethasone alone added at days 6 to 8 reduced fibroblast numbers, but not the total cell numbers (data not shown).

  • In control cells in the absence of dexamethasone, 10% of the cells showed nuclear>cytoplasmic localization of GR-GFP.


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