Words similar to dexamethasone
Example sentences for: dexamethasone
How can you use “dexamethasone” in a sentence? Here are some example sentences to help you improve your vocabulary:
In contrast, following treatment with ISIS 15534, GR-GFP was localized in the nucleus without dexamethasone treatment.
To examine the role of autocrine IL-6 on NRP-152 and NRP-154 cells, we looked at the effect of dexamethasone treatment on IL-6 expression on both cell lines, and on high and low IL-6-expressing clones of NRP-154 cells.
3%), dexamethasone (0.
Several lines of evidence indicate that NF-κB is constitutively activated in cancer cells, suggesting that it plays an important role in tumorigenesis [ 30 ] . Activated glucocorticoid receptors have been shown to repress NF-κB-mediated gene expression [ 31 ] , and to cause a significant reduction in nuclear levels of p65 protein, a subunit of NF-κB [ 31 ] . A variety of mitogens, cytokines, and reactive oxygen intermediates have been shown to rapidly cause the translocation of NF-κB to the nucleus [ 30 31 32 ] , and the ability of dexamethasone to interfere with this translocation is blocked by prior treatment with the glucocorticoid antagonist RU 486 [ 30 ] . Based on these findings, it is plausible to speculate that exposure to RU 486 may interfere with the function of endogenous glucocorticoids as regulators of cell cycle, allowing the initiation and progression of malignant transformation of liver cells.
To develop P. carinii infection, Sprague-Dawley female rats were immunosuppressed with dexamethasone and then trans-tracheally inoculated with 0.2 ml of homogenate of an infected rat lung containing 1 × 10 6 P. carinii trophozoites or with a homogenate of uninfected rat lung as controls as described previously [ 33].
Loading...