Example sentences for: dexamethasone

How can you use “dexamethasone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the following experiments, we used dexamethasone-free medium, and also treated the serum twice with activated charcoal, to remove endogenous steroids (stripped serum), then added defined amounts of dexamethasone for carying out the experiments.

  • We observed that dexamethasone treatment of NRP-152 cells inhibited IL-6 synthesis without affecting NRP-152 growth, as expected.

  • On the other hand, apoptosis was ruled out as a mechanism to explain the differential down-regulation of CD4 and CD8 by PMA and cAMP, on the grounds of two independent observations: (a) After a maximum of 4.0 hr incubation with either PMA or cAMP+ IBMX the cell viability was the same as the untreated controls (usually between 90-95%); (b) Treatment with dexamethasone, which is a known pro-apoptotic molecule did not have any effects on the expression of either CD4 or CD8 (data not shown) and; (c) As demonstrated earlier in the murine system, TCR engagement of CD4 +CD8 +induces positive selection but not apoptosis [ 12 ]

  • By contrast, the percentage of cells showing more nuclear than cytoplasmic distribution of GR-GFP was ~ 93%, ~ 88% and ~ 98% in cells treated with either dexamethasone, ISIS 15534, or ISIS 15534 and dexamethasone, respectively.

  • Dexamethasone is known to inhibit IL-6 synthesis by acting at the steroid-response elements of the IL-6 promoter . NRP-152 and NRP-154 cells were routinely grown in the presence of dexamethasone, so the effect on proliferation was not quantified.


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