Example sentences for: deoxycytidine

How can you use “deoxycytidine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Transcriptional silencing of genes resulting from DNA hypermethylation of CpG islands is reversed by treatment with the hypo-methylating agent 5-aza-2'-deoxycytidine and HDAC-inhibiting agent n-butyrate in a dose and duration-dependent manner.

  • We found that 5-Aza-2'-deoxycytidine treatment alone or in combination with n-butyrate resulted in reactivation of gene expression in most cell lines that showed promoter methylation.

  • The SW756 cell line with methylation and one of the two unmethylated cell lines showed reactivated expression upon treatment with 5-Aza-2' deoxycytidine or in combination with n-butyrate, but not with n-butyrate alone.

  • The MGMT gene exhibited promoter hypermethylation in four of the cell lines, which upon treatment with 5-Aza-2' deoxycytidine showed reactivation of expression in three (2102E-R, 833K-E, and Tera-2).

  • One cell line (T-218A) showed no promoter hypermethylation of MGMT by MSP and no detectable levels of mRNA expression by RT-PCR but expression was reactivated after 5-Aza-2' deoxycytidine treatment.


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