Example sentences for: deoxycytidine

How can you use “deoxycytidine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cell lines were treated with demethylating agent 5-Aza-2' deoxycytidine (Sigma) for five days at a concentration of 2 to 5 μM, HDAC-inhibiting agent n-butyrate at a final concentration of 5 μM for the last 24 hours or a combination of both.

  • The effect of methylation on gene expression was similarly assessed on total RNA isolated from cell lines treated with the demethylating agent 5-Aza-2' deoxycytidine (Sigma) for five days at a concentration of 2-5 μM.

  • Both methylated cell lines (HT-3 and SiHa) and three (C-33A, MS751, and ME-180) of the four unmethylated cell lines showed reactivation upon exposure to 5-Aza-2' deoxycytidine or in combination with n-butyrate.

  • We also showed that the hypermethylation leads to loss of expression in most of the genes and reactivate upon treatment with demethylating drug 5-Aza-2' deoxycytidine.

  • Transcriptional silencing of genes resulting from DNA hypermethylation of CpG islands is reversed by treatment of the hypo-methylating agent 5-aza-2'-deoxycytidine in a dose and duration-dependent manner.


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