Words similar to demonstrating
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Example sentences for: demonstrating
How can you use “demonstrating” in a sentence? Here are some example sentences to help you improve your vocabulary:
Valproic acid (VA) is a well-known teratogen in both animals and humans, with a 5-fold occurrence of spina bifida (SB) in pregnant women exposed to the drug [ 1 ] . The mechanism by which VA produces SB is unknown but inhibition of folic acid metabolism is one hypothesis [ 2 3 ] . Some investigators have brought the folic acid hypothesis into question by demonstrating that folic acid supplementation has no effect on VA exposed embryos in-vitro [ 4 5 ] . These studies suggest that another mechanism may be responsible for the production of SB by VA.
This is supported by intra-axonal recording of 1° muscle spindles demonstrating increased discharge with inspiration during tidal breathing in the cat [ 3 ] . While it is known that intercostal mechanoreceptors are sensitive to muscle motion, the specific afferent response to independently controlled changes in muscle displacement and velocity over the tidal volume range of rib motion is unknown.
3E,3F), demonstrating the difficulty of assigning significance to these in silico results.
To identify a group of rats as demonstrating paw preference, 7 of 10 rats had to be observed reaching in the same direction.
Fas contains a single transmembrane domain and belongs to the tumor necrosis factor (TNF)/nerve growth factor family [ 8 ] . FasL contains a single transmembrane domain and is also a member of the same TNF family [ 9 ] . A soluble form of FasL has been described, but appears to be less capable of inducing apoptosis, when compared with the bound form [ 10 11 ] . The binding of FasL with Fas initiates receptor oligomerization, which recruits Fas-associated death domain (FADD) [ 12 ] . FADD binds procaspase-8 and permits activation of caspase-8 through self-cleavage [ 13 ] . Caspase-8 activates the effector caspases, which commits the cell to the orderly process of apoptosis [ 14 15 ] . In addition, caspase-8 cleaves Bcl-2-interactive-death-agonist (Bid) [ 16 ] . Truncated Bid localizes to the mitochondria and promotes cytochrome c release; this process also serves as a major apoptotic-signaling pathway for Fas [ 16 17 18 ] . Depending upon the amount of caspase-8 that is activated, the predominant pathway can be either Bid cleavage with subsequent mitochondrial release of cytochrome c or activation of the effector caspase pathway [ 18 ] . Resident cells of the kidney express both Fas and FasL and Fas/FasL signaling is functional in these cells [ 19 20 21 22 23 24 ] . A recent review by Ortiz and associates [ 25 ] noted that the combined literature demonstrating participation of Fas/FasL pathway in renal injury essentially fulfilled Koch's postulates.
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