Words similar to dementia
Example sentences for: dementia
How can you use “dementia” in a sentence? Here are some example sentences to help you improve your vocabulary:
It should be noted that this cut-point of 27 on the MMSE is considerably above the cut-point of 23 that is commonly used to identify dementia.
The available research regarding cognitive function and phytoestrogens suggests that large amounts of phytoestrogens, consumed as tofu, have an adverse influence on cognitive ability in men, where decreased brain weight, increased ventricular size and dementia have been reported [ 44 ] . In ovariectomized female rats, on the other hand, phytoestrogen treatments resulted in a dose-dependent improvement of VSM [ 45 ] . This improvement in cognitive ability in phytoestrogen treated females may be due in part to the increased presence of choline acetyltransferase messenger RNA in the frontal cortex, which has been shown to be associated with protection and enhancement of cognitive function [ 45 ] . Furthermore, we have shown that phytoestrogens significantly affect the brain calcium-binding protein calbindin (CALB), which acts as a buffer by binding intracellular calcium and plays an important role in mediating cell proliferation, programmed cell death (apoptosis), and neurotoxicity [ 48 49 50 51 52 ] . This neuroprotective mechanism via CALB appears to be important in neurological disorders such as Parkinson's disease and Huntington's disease [ 48 49 50 51 52 ] . Additionally, Cyclooxygenase-2 (COX-2) seems to play an important role in mediating functional neuronal maturation and responses to certain stimuli in the brain [ 53 54 55 ] . The expression of COX-2 is associated with key pathophysiologic events in Alzheimer's disease: deposition of beta-amyloid protein in neuritic plaques within the hippocampus and cortex [ 53 54 55 ] . Of particular importance to this study is the fact that COX-2 has been shown to be influenced by steroidal hormones [ 53 54 55 ] . Therefore, the expression of COX-2 in the frontal cortex may also be hormonally regulated and relevant to cognitive decline.
This finding is in line with the literature, which suggests that individuals who have cognitive deficits are at greater risk for exhibiting behavioral problems in long-term and other non-acute settings [ 24 ] . Investigators have found lower MMSE scores at admission predictive of functional decline following acute medical illness and hospitalization [ 26 ] . Additionally, cognitive impairment is associated with the development of delirium during hospitalization, which in turn, can result in a variety of behavioral problems [ 27 ] . However, in these studies, patients usually had cognitive impairment indicative of dementia, whereas the current study suggests that among hospitalized elderly, a MMSE score of less than 27 places a patient at increased risk of behavioral problems.
So far, we have little evidence that mental practice will help prevent the development of dementia.
1941, 19th ed.: A generic designation for mental deterioration, less frequently used than formerly, except in the term dementia praecox.
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