Example sentences for: degenerative

How can you use “degenerative” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In simple terms, if the differentiation of tissue cells is suppressed, immature cells will persist during adulthood (muscular dystrophy), and if it is accelerated, premature aging will occur (degenerative diseases) [ 9].

  • In addition, the decidual cells, which are known to exhibit degenerative changes at term [ 44 ] , show marked diminution of cytoplasmic ERβ.

  • Microglial cells are resident macrophages in the central nervous system, and LHR expression has been described in other types of human resident macrophages (ovary, decidua, endometrium and corpora lutea) [ 22 33 ] . Pathological activation of microglia has been reported in a wide range of conditions such as Alzheimer's disease, cerebral ischemia, prion diseases, multiple sclerosis, AIDS dementia, and other degenerative neurological diseases [ 70 71 ] . Some of these degenerative diseases are associated with advanced age and high levels of circulating LH.

  • LHR immunoreactivity in porcine fallopian tubes was confined to the epithelium and smooth muscle cells, and in vitro LH treatment caused relaxation of the oviduct [ 35 ] . Also, LHR stimulation plays a role in the induction and maintenance of myometrial quiescence [ 36 37 38 ] . Since smooth muscles belong among important compartments of the pelvic floor, high LH levels after menopause might be involved in the increased incidence of pelvic floor disorders, a common condition in postmenopausal women [ 39 ] . Since the brain was reported to express functional LHR [ 29 30 ] , there is also a possibility that high LH levels in aging individuals may in some way participate in the development and progression of neurodegenerative process of several degenerative neurological diseases, including Alzheimer's disease.

  • Once AEV is achieved, there will be no going back: rejuvenation research will be intense forever thereafter and will anticipate and remedy the life-threatening degenerative changes appearing at newly achieved ages with ever-increasing efficacy and lead time.


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