Example sentences for: degeneration

How can you use “degeneration” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The changes in sequences underlying initiation of both transcription and translation, as well as the loss of regulatory proteins [ 8], give an impression of genome-wide degeneration of regulatory functions in Buchnera.

  • It is interesting to note, however, that in newborn mice a brief local application of 2 mM domoic acid to the exposed cortical surface led to a massive degeneration of AMPA/KA GluR receptor positive Cajal-Retzius neurons [ 44 ] , severe impairment of cortical neuronal migration in vivo and malformation of the domoic acid-treated neocortex [ 44 ] . Thus, because 1 mM domoic acid was clearly toxic to cerebellar granule neurons both in vitro (our current study) and in vivo [ 44 ] , we selected 1 mM domoic acid for the experiments with rat neonatal microglia reported herein.

  • These features bare resemblances to mitochondrial degeneration in other neurodegenerative conditions, including Alzheimer's disease [ 79 ] , prion disease [ 80 ] , Rett syndrome [ 81 ] , excitotoxic neuronal death [ 70 ] and Mn ++superoxide dismutase (SOD2) deletion [ 82 ] . Although in none of these conditions are sufficiently detailed observations available for a comprehensive comparison, MVISE could play a role in other neurodegenerative disorders.

  • Wallerian degeneration normally occurs much faster in peripheral nerves than in white matter [ 46, 47, 48].

  • Color fundus photographs have been routinely employed for diagnostic purposes for many years, and fundus photo gradings are central to clinical studies of macular disease [ 1 2 ] . The natural history of age-related macular degeneration (AMD), the leading cause of blindness in the developed world [ 3 ] , is in particular tied to that of subretinal deposits known as drusen [ 4 5 6 7 8 9 10 11 12 ] . Drusen are key in the classification of AMD, hence the importance of drusen identification and measurement in clinical studies.


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