Words similar to degenerate

Example sentences for: degenerate

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To compute our FCA on gene codon composition, we used absolute codon frequencies, without considering the three stop codons or the ATG and TGG codons, which are not degenerate.
Other highly conserved regions include TM1, TM2 and TM7; the last two domains are routinely used in the design of family-specific degenerate oligonucleotide primers for PCR amplification of ORs.
Initial surveys of natural populations of Drosophila melanogaster showing that TE insertion alleles are in uniformly low frequency seemed to negate the adaptive hypothesis [ 6 ] . However, the sporadic discovery of degenerate TEs or TE fragments as critical components of functional genes in both plants and animals was sufficient to keep the adaptive hypothesis alive throughout the pre-genomic era [ 7 8 9 10 11 ] .
We thus obtained a matrix consisting of 59 columns (corresponding to the 59 degenerate codons) and as many rows as sequences analyzed.
At first, we made degenerate deoxyoligonuclotide primers corresponding to the conserved peptide sequences GDXHGQ and GDXVDRG of PPs [ 17 ] . An approximately 120 bp PCR product, obtained by using these primers with the Pf 3D7 genomic DNA as template, was cloned in the pGEM-T vector (Promega) using the T/A cloning strategy.