Words similar to deacetylase

Example sentences for: deacetylase

How can you use “deacetylase” in a sentence? Here are some example sentences to help you improve your vocabulary:

4B) were examined to identify the potency of SAHA as a histone deacetylase inhibitor on mammary epithelial cells.
It was reported that some agents, e.g. histone deacetylase inhibitors [ 14 ] or DNA methylation inhibitors [ 15 ] , can rescue the IFNg inducibility of MHCII in cultured tumor cells.
Sir2 (the mammalian homolog is SIRT1) is a nicotinamide-adenine-dinucleotide-dependent histone deacetylase that interacts with numerous transcription factors to silence gene transcription.
The resulting retinoblastoma protein (Rb)-E2F interaction not only blocks transcriptional activation by E2F, but also forms an active transcriptional repressor complex at the promoter of cell cycle genes that can block transcription by recruiting histone deacetylase (HDAC) and remodeling chromatin [ 11, 12, 13, 14].
Thus, histone deacetylase inhibitors - Butyrate and Trichostatin A - can rescue MHCII-inducibility in bladder carcinoma cells [ 14 ] and restore constitutive MHCII expression in plasmacytoma cells [ 35 ] . In addition to acetylation, transcriptional activity of chromatin is also regulated through phosphorylation (reviewed in Ref.