Words similar to deacetylase
Example sentences for: deacetylase
How can you use “deacetylase” in a sentence? Here are some example sentences to help you improve your vocabulary:
The resulting retinoblastoma protein (Rb)-E2F interaction not only blocks transcriptional activation by E2F, but also forms an active transcriptional repressor complex at the promoter of cell cycle genes that can block transcription by recruiting histone deacetylase (HDAC) and remodeling chromatin [ 11, 12, 13, 14].
We therefore suggest that the dose and time regimen for histone deacetylase inhibitors, such as SAHA, may have to consider the p53 status of breast cancers.
A PSI-BLAST search started with the N-terminal SBHM from the Aquifex aeolicus DDRP β' subunit detected several SBHMs from proteins other than the β' subunit, such as acetylornithine deacetylase (E = 2 × 10 -7, iteration 2), the C-terminal region of bacterial cytochrome F (E = 10 -4, iteration 2), biotin carboxyl carrier domain of biotin transcarboxylases (E = 6 × 10 -4, iteration 2) and the phosphotransferase system enzyme II (E = 10 -3, iteration 2).
We also found evidence that promoter methylation inactivates gene expression in CC and exposure to methylation and/or histone deacetylase (HDAC)-inhibiting agents reactivate the gene expression.
4B) were examined to identify the potency of SAHA as a histone deacetylase inhibitor on mammary epithelial cells.