Words similar to deacetylase
Example sentences for: deacetylase
How can you use “deacetylase” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, histone deacetylase inhibitors - Butyrate and Trichostatin A - can rescue MHCII-inducibility in bladder carcinoma cells [ 14 ] and restore constitutive MHCII expression in plasmacytoma cells [ 35 ] . In addition to acetylation, transcriptional activity of chromatin is also regulated through phosphorylation (reviewed in Ref.
We also found evidence that promoter methylation inactivates gene expression in CC and exposure to methylation and/or histone deacetylase (HDAC)-inhibiting agents reactivate the gene expression.
We therefore suggest that the dose and time regimen for histone deacetylase inhibitors, such as SAHA, may have to consider the p53 status of breast cancers.
It was reported that some agents, e.g. histone deacetylase inhibitors [ 14 ] or DNA methylation inhibitors [ 15 ] , can rescue the IFNg inducibility of MHCII in cultured tumor cells.
The resulting retinoblastoma protein (Rb)-E2F interaction not only blocks transcriptional activation by E2F, but also forms an active transcriptional repressor complex at the promoter of cell cycle genes that can block transcription by recruiting histone deacetylase (HDAC) and remodeling chromatin [ 11, 12, 13, 14].
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