Example sentences for: ddrp

How can you use “ddrp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • An alternative scenario holds that the RDRPs are ancient enzymes that diverged from the evolutionary precursor of DDRP at a very early, pre-LUCA stage of evolution, albeit after the duplication that led to the differentiation of the β and β' versions of the DPBB domain.

  • One possibility is that the RDRP module has emerged at the onset of the evolution of eukaryotes through extreme sequence divergence following a duplication of the DDRP β' subunit.

  • Examination of the recently solved structures of the DDRP showed that, although β' subunit is a large protein, the active site containing the DxDGD motif mapped to a small, compact β-barrel domain.

  • In fact, it appears likely that the ancestral protein RNA polymerase, at the time of the differentiation of the β-type and β'-type DPBB domains, functioned as an RDRP because DNA probably had not evolved by that stage [ 96 ] . The switch of the ancestral enzyme to the DDRP activity and the emergence of the evolutionary precursor of RDRP might be tentatively linked to one another and associated with the advent of DNA.

  • The SCOP database, while classifying the DDRP subunits in the multidomain category, recognizes two DPBBs in the DDRP complex.


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