Example sentences for: ddrp
How can you use “ddrp” in a sentence? Here are some example sentences to help you improve your vocabulary:
Nevertheless, DDRP is one of the most conserved enzymes, which is represented, without exception, in all cellular life forms [ 31 32 ] . The DDRP complex from most organisms consists of 5 to 15 polypeptides.
In the archaeo-eukaryotic lineage, another domain, apparently derived through duplication of the dimerization domain of the DDRP α-subunit, was inserted into the C-terminal region of the β' subunit.
An alignment of the SBHM domains from the DDRP β subunit with the previously identified SBHMs showed conservation of most residues characteristic of the SBHM superfamily (Fig.
The predicted DPBB domains of the RDRPs differ from most of the DPBB domains of DDRP β' subunits in that the former lack a long and variable, in both length and sequence, insert between strands 2 and 3 that is characteristic of the latter (Fig.
Visual examination of the structure of this insert domain revealed a topology with elements of both a sandwich and a barrel, and two "waist"-like structures that are characteristic of the sandwich-barrel hybrid motif (SBHM) fold [ 75 76 ] (see also the SCOP database [ 65 ] ). The SBHM fold is present in biotin/lipoate carrier domains and their homologs found in a variety of enzymes and transporters [ 76 ] . A DALI search with this insert domain from the β subunit of Thermus DDRP showed similarity to the SBHMs from various biotin/lipoate-binding enzymes, such as acetyl-CoA carboxylase (1bdo) or dihydrolipoamide acetyltransferase (1iyu) with Z scores of ~6 and RMSD ~2.
Loading...