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Example sentences for: ddc

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This outcome has become associated with a population genetic model known as the Duplication–Degeneration–Complementation (DDC) model, which focuses attention on the regulatory changes after duplication (Force et al.
As CDY is a retrogene (see above) that has not been duplicated together with its ancestral regulatory sequences, it is clear that the DDC model is not the only route by which to achieve spatial partitioning of ancestral expression patterns.
Rad26 is a regulatory subunit of the Rad26/Rad3 complex that is required for Rad3 kinase activity [ 18 ] . Following DNA damage, Rad26 undergoes Rad3-dependent phosphorylation [ 17 ] . Rad26 is a 70 kDa protein containing little informative sequence information beyond a predicted coiled-coil region and a basic stretch that resembles a nuclear localization signal [ 13 32 ] . Functionally conserved proteins with very weak sequence similarity have been found in human (ATRIP) [ 35 ] , S. cerevisiae LCD1 (aka DDC2 and PIE1) [ 36 37 38 ] and A. nidulans (UVSD) [ 32 ] .
Under the DDC model, greater regulatory complexity bestows greater potential for subfunctionalization (Force et al.