Words similar to daz

Example sentences for: daz

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Deletion of the DAZ genes is found in about 10% of infertile males with idiopathic azoospermia [ 2 ] , and disruption of Dazl1 causes infertility in both male and female mice [ 6 ] . Mutations in the DAZ family members of Drosophila [ 7 ] , C. elegans [ 8 ] , and Xenopus [ 9 ] also affect the fertility in either males, females, or both sexes.
DAZ and DAZL are expressed in the nucleus and cytoplasm of primordial germ cells and spermatogonia, and in the cytoplasm of meiotic spermatocytes [ 6 10 ] . BOULE is expressed later, in the cytoplasm of pachytene spermatocytes [ 5 ] . Genetic and biochemical studies suggest a role for the DAZ family in the regulation of mRNA translation.
The family includes the Y-linked DAZ genes that are present only in great apes and old world monkeys [ 3 ] , and the autosomal DAZL1 (DAZ-like 1) and BOULE genes [ 4 5 ] in all mammals.
In an attempt to elucidate the function of the DAZ gene family and to understanding the mechanisms of its action, we used a yeast two-hybrid system to isolate two human genes encoding DAZ associated proteins (DAZAPs) [ 14 ] . One of them, DAZAP1, is expressed predominantly in testes.
The DAZAP1 protein interacted with both DAZ and DAZL in vitro.