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Example sentences for: daudin

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We start however with the understanding that the sequence is fundamentally nonstationary, exhibiting statistically significant variations in base frequencies between non-overlapping windows [ 1 2 ] . Locally or globally estimated Markov models may describe it better than assuming that the bases are independent and identically distributed [ 19 ] but they fail to reflect the salient features of natural sequences [ 20 ] . For example, Robin and Daudin [ 21 ] compared the frequency of a specific motif in the genome sequence of Haemophilus influenzae to Markovian predictions and found that the observed frequencies were everywhere higher than predicted.