Words similar to damage-inducible

Example sentences for: damage-inducible

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C/EBPα binds to and activates transcription of the gene promoter for the p21 inhibitor of cyclin-dependent kinase (CDK) [ 37 ] . This led to speculation that p21 gene activation may contribute to cell cycle arrest by C/EBPα [ 37 ] . Similarly, suppression of mitotic growth during adipocyte differentiation was associated with C/EBPα activation of the promoters of gadd45 (growth arrest and DNA damage-inducible gene 45), gas2 and gas3 (growth arrest-associated genes 2 and 3) [ 5 6 38 39 ] . However, C/EBPα mutants defective in DNA binding still blocked proliferation [ 25 33 ] . This suggested that direct promoter activation was unnecessary, or redundant, for C/EBPα proliferation arrest [ 18 ] .