Example sentences for: damage-induced

How can you use “damage-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • DNA repair activities may take place at these foci since BRCA1 has been shown to co-localize with ATR in damage-induced foci [ 58 ] . Using elegant methods to test for direct association of DNA damage checkpoint proteins at double strand breaks in vivo , other groups have shown that MEC1 Rad3-HA and LCD1 Rad26-GFP localize to sites of DNA damage [ 59 60 ] . However, MEC1 was required for this re-localization of LCD1-GFP in vivo [ 60 ] . Thus, while re-localization of Rad26/Rad3-related complexes to sites of DNA repair may be evolutionarily conserved, the regulation of these complexes is not.

  • These DNA damage-induced phosphorylations of p53 block the binding of mdm2 to the N-terminal of the p53 protein [ 18].

  • For example, p53's DNA binding activity is increased by the DNA damage-induced acetylation of the C-terminal of p53 [ 16, 19], and this acetylation requires the prior phosphorylation of the N-terminal of p53 [ 16].


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