Words similar to cyclophosphamide
Example sentences for: cyclophosphamide
How can you use “cyclophosphamide” in a sentence? Here are some example sentences to help you improve your vocabulary:
In Silber's patient sample, one-third of the patients were treated with the less myelosuppressive CMF (cyclophosphamide, methotrexate, fluorouracil) chemotherapy regimen, and the CAF (cyclophosphamide, doxorubicin, fluorouracil) regimen consisted of 30 mg/m 2compared with the 50 mg/m 2CAF regimen used in our validation sample.
All patients were treated with the FAC (fluorouracil, doxorubicin, cyclophosphamide) regimen that consisted of 50 mg/m 2doxorubicin given as a continuous infusion over 72 hours starting on day 1, 500 mg/m 2cyclophosphamide intravenously on day 1, and 500 mg/m 2fluorouracil intravenously on days 1 and 4. Treatment was given every 3 or 4 weeks for a total of six cycles.
Treatment of L1210/CPA cells in vitro with 50 μM DEAB abolished the tumor cells' resistance to 4-HC [ 19 ] . DEAB also exhibited in vivo efficacy as a ALDH1A1 inhibitor, as demonstrated by the toxicity to the intestinal crypt cells in mice receiving co-injections of DEAB and cyclophosphamide [ 21 ] . More recently, DEAB has been used to demonstrate that overexpression of human ALDH1A1 in transfected cell lines is sufficient to cause cellular resistance to the oxazaphosphorines [ 22 ] and 4-HC [ 23 ] . DEAB has also been an effective reagent in fluorescent-activated cell sorting (FACS) techniques to isolate human hematopoietic stem cells based on the expression of ALDH1A1 activity [ 5 6 ] . In contrast to DEAB and DPAB, daidzin - a natural product isolated from Pueraria lobata (the Kudzu plant) - shows specificity for inhibiting ALDH2 at concentrations similar to that of DPAB used to inhibit ALDH1A1 [ 24 25 ] . An inhibitor specific for ALDH1A2 has not yet been reported.
AGCN = average gene copy number; CART = Classification and Regression Trees; CMF = cyclophosphamide, methotrexate, 5-fluorouracil; DFS = disease-free survival; NNBC = node-negative breast cancer; FEC = fluorouracil, epirubicin, cyclophosphamide; OS = overall survival; PCR = poly-merase chain reaction.
Medications including cyclosporine, cyclophosphamide, and any DMARD were not allowed.
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