Example sentences for: cullins

How can you use “cullins” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, it remained unclear whether this reflects global control of multiple cullins by Csn1p as part of the entire CSN complex.

  • All human cullins have been shown to assemble into complexes possessing polyubiquitylation activity in vitro [ 9, 26].

  • In addition to CUL1, the human genome contains at least five other cullins, CUL 2, 3, 4A, 4B, and 5. This diversity is partially recapitulated in S. pombe , which encodes pcu3 and pcu4 , homologues of human CUL3 and CUL4, for which there are no direct correlates in budding yeast [ 6].

  • Similarly, the fission yeast cullins Pcu1p and Pcu4p are neddylated, and neddylation is critical for their function in vivo . [ 5].

  • 2C, 2D), where both cullins seem constitutively neddylated, argues against a critical role for dynamic cycles of neddylation and deneddylation in cullin function in fission yeast.


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