Words similar to cullins
Example sentences for: cullins
How can you use “cullins” in a sentence? Here are some example sentences to help you improve your vocabulary:
2C, 2D), where both cullins seem constitutively neddylated, argues against a critical role for dynamic cycles of neddylation and deneddylation in cullin function in fission yeast.
Second, replacing lysine 729, which is homologous to the conserved neddylation sites in other cullins, with arginine, completely abolished the slower migrating, modified form of Pcu3p (Fig.
Thus, as with other S. pombe cullins [ 5], Pcu3p undergoes covalent modification by ubiquitin-like Ned8p at lysine 729.
All human cullins interact with HRT1/RBX1/ROC1 [ 7], are modified by NEDD8 [ 8], and have ubiquitin ligase activity in vitro [ 9].
In addition to CUL1, the human genome contains at least five other cullins, CUL 2, 3, 4A, 4B, and 5. This diversity is partially recapitulated in S. pombe , which encodes pcu3 and pcu4 , homologues of human CUL3 and CUL4, for which there are no direct correlates in budding yeast [ 6].
Loading...