Words similar to cullins

Example sentences for: cullins

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Similarly, the fission yeast cullins Pcu1p and Pcu4p are neddylated, and neddylation is critical for their function in vivo . [ 5].
All human cullins have been shown to assemble into complexes possessing polyubiquitylation activity in vitro [ 9, 26].
In addition to CUL1, the human genome contains at least five other cullins, CUL 2, 3, 4A, 4B, and 5. This diversity is partially recapitulated in S. pombe , which encodes pcu3 and pcu4 , homologues of human CUL3 and CUL4, for which there are no direct correlates in budding yeast [ 6].
2C, 2D), where both cullins seem constitutively neddylated, argues against a critical role for dynamic cycles of neddylation and deneddylation in cullin function in fission yeast.
Second, replacing lysine 729, which is homologous to the conserved neddylation sites in other cullins, with arginine, completely abolished the slower migrating, modified form of Pcu3p (Fig.