Example sentences for: culminate

How can you use “culminate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These signaling pathways culminate in the activation of specific transcription factors, so that there must be both shared target genes, as well as genes unique to antigen or IL-2 signaling.

  • But otherwise there is some pleasant geometry, some mostly unremarkable portraits, some jazzy fashion shots that culminate in Helmut Newton's high-gloss simulated sadism.

  • In May, the Justice Department began shaping plans for building a budget for fiscal year 2003, the process that would usually culminate in an administration proposal at the beginning of 2002.

  • The plan would culminate at the end of the year in a Barak-Clinton-Arafat summit to declare an "agreed framework for the permanent settlement" or, failing that, a declaration of principles outlining the steps toward a settlement.

  • SLC/CCL21, normally expressed in high endothelial venules and in T cell zones of spleen and lymph nodes, strongly attracts T cells and dendritic cells (DC) [ 1 2 3 4 5 6 7 8 ] . SLC/CCL21 recruits both naïve lymphocytes and antigen stimulated DC into T cell zones of secondary lymphoid organs, co-localizing these early immune response constituents that culminate in cognate T cell activation [ 1 ] . The capacity to facilitate the co-localization of both DC and T cells forms a strong rationale for the use of SLC/CCL21 in cancer therapy.


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