Example sentences for: cullin

How can you use “cullin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The cullin/RING family of ubiquitin ligases comprises a multifunctional set of enzymes controlling the stability and activity of cell cycle regulators, transcription factors, and signaling proteins (reviewed in ref.

  • SCF: SKP1/Cullin/F-box protein complex

  • This mutant accumulates Pcu1p exclusively in a form carrying the stimulatory Nedd8p modification, due to a defect in COP9/signalosome-mediated cullin deneddylation [ 24 25 ] . Replacing wild-type ubiquitin by a mutant lacking all lysine residues prevented the formation of high molecular weight products (Fig.

  • 2A), suggesting that CSN has a general role in the control of cullin neddylation in fission yeast.

  • 2A, and data not shown), also suggests that control of cullin neddylation results from cooperation of multiple CSN components rather than from the activity of a single catalytic subunit.


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