Words similar to cullin
Example sentences for: cullin
How can you use “cullin” in a sentence? Here are some example sentences to help you improve your vocabulary:
2C, 2D), where both cullins seem constitutively neddylated, argues against a critical role for dynamic cycles of neddylation and deneddylation in cullin function in fission yeast.
SCF = SKP1/Cullin/F-box protein complex
Thus, cullin regulation through modulation of the balance of Ned8p modification appears to require the entire CSN complex.
2A), suggesting that CSN has a general role in the control of cullin neddylation in fission yeast.
COP10, which has been shown to interact with AtCOP1 in yeast two-hybrid experiment, encodes a ubiquitin conjugating enzyme (E2) variant [ 44 ] . The COP9 signalosome, an eight-subunit complex homologous to the lid subcomplex of the 26 S proteasome [ 45 ] , directly associates with SCF E3 complex and promotes deneddylation of the cullin subunit of SCF in both plant and animal cells [ 46 47 48 49 ] . The exact relationship between COP1 and the COP9 signalosome remains obscure; it is known, however, that in Arabidopsis the COP9 signalosome is required for COP1 to accumulate in the nucleus in the dark [ 29 ] . Although COP1 most likely plays a role in regulating protein degradation, attempts in reconstituting ubiquitination of HY5 by AtCOP1 have been unsuccessful.
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